| BCSS | DFSS | |||||||
| Univariate Analysis | Multivariate Analysis | Univariate Analysis | Multivariate Analysis | |||||
| OR (95% CI) | P-value | OR (95% CI) | P-value | OR (95% CI) | P-value | OR (95% CI) | P-value | |
| Age (years) |
| <0.001 |
| <0.001 |
| <0.001 |
| <0.001 |
| <35 | 1.604 (1.327 - 1.938) |
| 1.529 (1.264 - 1.850) |
| 1.425 (1.234 - 1.645) |
| 1.376 (1.191 - 1.589) |
|
| ≥35 | 1 (ref) |
| 1 (ref) |
| 1 (ref) |
| 1 (ref) |
|
| T stage |
| <0.001 |
| <0.001 |
| <0.001 |
| <0.001 |
| T1 | 1 (ref) |
| 1 (ref) |
| 1 (ref) |
| 1 (ref) |
|
| T2 | 2.657 (2.106 - 3.352) |
| 2.372 (1.859 - 3.026) |
| 1.574 (1.367 - 1.813) |
| 1.576 (1.368 - 1.816) |
|
| T3 | 4.922 (3.772 - 6.424) |
| 3.909 (2.858 - 5.348) |
| 2.139 (1.77 - 2.584) |
| 2.121 (1.755 - 2.562) |
|
| T4 | 3.134 (2.174 - 4.519) |
| 2.483 (1.647 - 3.744) |
| 1.420 (1.076 - 1.872) |
| 1.396 (1.059 - 1.842) |
|
| Unknown | 4.129 (2.149 - 7.934) |
| 3.386 (1.744 - 6.576) |
| 1.800 (1.052 - 3.078) |
| 1.770 (1.034 - 3.029) |
|
| Lymph node status |
| <0.001 |
| 0.001 |
| 0.003 |
|
|
| N0 | 1 (ref) |
|
|
| 1 (ref) |
|
|
|
| N1 | 1.833 (1.493 - 2.251) |
| 1.451 (1.174 - 1.792) |
| 1.102 (0.958 - 1.268) |
|
|
|
| N2 | 2.514 (2.002 - 3.156) |
| 1.600 (1.238 - 2.068) |
| 1.241 (1.045 - 1.473) |
|
|
|
| N3 | 2.664 (2.08 - 3.411) |
| 1.485 (1.11 - 1.986) |
| 1.383 (1.146 - 1.669) |
|
|
|
| Tumor stage |
| <0.001 |
| 0.503 |
| <0.001 |
|
|
| 1 | 1 (ref) |
|
|
| 1 (ref) |
|
|
|
| 2 | 2.773 (2.067 - 3.72) |
|
|
| 1.543 (1.31 - 1.816) |
|
|
|
| 3 | 4.576 (3.407 - 6.144) |
|
|
| 1.748 (1.469 - 2.081) |
|
|
|
| Unknown | 3.476 (1.258 - 9.605) |
|
|
| 1.149 (0.473 - 2.791) |
|
|
|
| Histologic grade |
| 0.177 |
| - |
| 0.001 |
| 0.002 |
| G1 | 1 (ref) |
|
|
| 1 (ref) |
| 1 (ref) |
|
| G2 | 0.997 (0.766 - 1.299) |
|
|
| 1.040 (0.855 - 1.264) |
| 1.019 (0.838 - 1.239) |
|
| G3 | 1.192 (0.921 - 1.542) |
|
|
| 1.269 (1.049 - 1.535) |
| 1.232 (1.018 - 1.491) |
|
| Unknown | 1.230 (0.795 - 1.901) |
|
|
| 1.491 (1.095 - 2.029) |
| 1.497 (1.099 - 2.039) |
|
| ER |
| <0.001 |
| 0.827 |
| 0.010 |
| 0.029 |
| Positive | 1 (ref) |
|
|
| 1 (ref) |
| 1 (ref) |
|
| Negative | 0.701 (0.591 - 0.831) |
|
|
| 0.84 3 (0.74 - 0.959) |
| 0.865 (0.759 - 0.985) |
|
| PR |
| <0.001 |
| 0.782 |
| 0.048 |
|
|
| Positive | 1 (ref) |
|
|
| 1 (ref) |
|
|
|
| Negative | 0.726 (0.614 - 0.860) |
|
|
| 0.879 (0.773 - 0.999) |
|
|
|
| HER2 |
| <0.001 |
| 0.845 |
| 0.011 |
|
|
| Positive | 1 (ref) |
|
|
| 1 (ref) |
|
|
|
| Negative | 1.393 (1.144 - 1.695) |
|
|
| 1.237 (1.071 - 1.429) |
|
|
|
| Unknown | 1.366 (1.128 - 1.653) |
|
|
| 1.137 (0.986 - 1.31) |
|
|
|
| Ki-67(%) |
| 0.258 |
| - |
| 0.783 |
|
|
| <14% | 1 (ref) |
|
|
| 1 (ref) |
|
|
|
| ≥14% | 1.100 (0.933 - 1.298) |
|
|
| 1.009 (0.895 - 1.137) |
|
|
|