Placebo

Melatonin

Measurement

SBP

DBP

HR

SBP

DBP

HR

S

107.6 ± 1.4

62.1 ± 1.2

58.4 ± 1.4

109.6 ± 1.5

61.8 ± 1.1

60.6 ± 1.3

1

132.2 ± 5.7^*

78.7 ± 2.8^*

96.1 ± 4.5^*

118.8 ± 3.1^*

66.8 ± 3.1^*

82 ± 6.6

2

126.9 ± 3.6^*

79.5 ± 2.7^*

83.2 ± 5.6^*

124.4 ± 4.7^*

76 ± 3.4^*

84.3 ± 5.2^*

3

122.6 ± 3.6^*

77.4 ± 2.3^*

83.7 ± 5.4^*

120.5 ± 3.4^*

71.8 ± 3.2^*

81.4 ± 3.6^*

4

120.5 ± 3.5^*

75.2 ± 2.6^*

81.8 ± 5.4^*

119.4 ± 5^*

72.8 ± 2.8^*

83.1 ± 4.4^*

5

121.5 ± 4^*

72.7 ± 2.7^*

83.5 ± 4.9^*

116.4 ± 3.1^*

70.9 ± 3.7^*

84.5 ± 5.5^*

6

122.9 ± 3.8^*

72.6 ± 2.9^*

81.8 ± 4.4^*

114.6 ± 3.5^*

70.1 ± 3.5^*

86.5 ± 4.6^*

7

121.4 ± 3.2^*

70.4 ± 2.8^*

82.6 ± 4.7^*

113.3 ± 3.8

69.6 ± 3.5^*

86.7 ± 4.8^*

8

118.7 ± 3.7^*

70.9 ± 2.7^*

81.8 ± 4.6^*

115.3 ± 4.2^*

69.3 ± 3.4^*

83.3 ± 4.4^*

9

117.9 ± 3.1^*

69.3 ± 2.9^*

83.2 ± 4.6^*

115.7 ± 3.8^*

66.5 ± 3.2

85.3 ± 4.1^*

10

115.5 ± 3.1^*

67.4 ± 3^*

83.8 ± 4.6^*

114.8 ± 4.2^*

64.4 ± 3.2

85.5 ± 3.1^*

11

118.8 ± 3.3^*

66.3 ± 3.1

84 ± 5.1^*

114.6 ± 4.9^*

65.3 ± 3.4

83.1 ± 3^*

12

116.6 ± 3.5^*

68.6 ± 2.9^*

82.9 ± 4.4^*

118.4 ± 4.8^*

64.3 ± 2.8

80.3 ± 5.1^*

13

114.9 ± 2.7^*

67.8 ± 2.8^*

83.3 ± 4.3^*

116.1 ± 4.3^*

66.5 ± 3.5

84.5 ± 4.8^*

14

116.3 ± 3.5^*

64.4 ± 3.9

83.8 ± 4.9^*

112.5 ± 4.4

66 ± 3.6

83.4 ± 4.4^*

15

115.1 ± 4.1^*

63.8 ± 4.1

81 ± 5.1^*

111.1 ± 4.4

63.5 ± 4

83.6 ± 5.6^*

16

119.3 ± 3.8^*

68.3 ± 3.6^*

81.3 ± 4.4^*

111 ± 4.2

64 ± 3

83.9 ± 3.7^*

17

117.2 ± 4.2^*

67.8 ± 4.1

80.2 ± 4.4^*

114.1 ± 3.7

66.1 ± 2.9

83.4 ± 3.8^*

18

115.9 ± 4^*

67.8 ± 4.8

81.4 ± 4.8^*

114.9 ± 3.9

65.3 ± 3.1

83.3 ± 4.1^*

19

116.6 ± 4^*

69.6 ± 2.9^*

82.3 ± 6^*

116 ± 4.5^*

66.6 ± 3

84.8 ± 4.1^*

20

118.9 ± 3.2^*

69 ± 3^*

80.8 ± 4.6^*

115.5 ± 4.1^*

67.7 ± 3.1^*

86 ± 2.9^*

21

121 ± 5.6^*

69.2 ± 2.7^*

84.6 ± 4.6^*

111.9 ± 3.8

64.2 ± 2.5

81.5 ± 3.4^*