1) Age at disease onset < 40 years | Development of symptoms or findings related to Takayasu arteritis at age < 40 years |
2) Claudication of extremities | Development and worsening of fatigue and discomfort in muscles of 1 or more extremity while in use, especially the upper extremities |
3) Decreased brachial artery pulse | Decreased pulsation of 1 or both brachial arteries |
4) BP difference > 10 mm Hg | Difference of >10 mm Hg in systolic blood pressure between arms |
5) Bruit over subclavian arteries or aorta | Bruit audible on auscultation over 1 or both subclavian arteries or abdominal aorta |
6) Arteriogram abnormality | Arteriographic narrowing or occlusion of the entire aorta, its primary branches, or large arteries in the proximal upper or lower extremities, not due to arteriosclerosis, fibromuscular dysplasia, or similar causes; changes usually focal or segmental |