Variable

Untreated (n = 52)

Treated (n = 168)

Dipper

n = 13

Non-dipper

n = 13

Reverse dipper

n = 6

p

Dipper

n = 50

Non-dipper

n = 101

Reverse dipper

n = 17

p

Hb, g/dl

12.7 ± 1.1

12.7 ± 1.5

11.9 ± 1.1

0.356

12.8 ± 1.8

12.3 ± 1.5

12.2 ± 2.1

0.322

Anemia, n (%)

0 (0.0)

3 (9.70)

1 (16.7)

0.294

4 (11.1)

11 (15.5)

5 (35.7)

0.015

HbA1c, %

5.1 ± 1.1

6.5 ± 1.2

12.5 ± 1.6

0.023

7.3 ± 1.5

7.5 ± 1.7

5.9 ± 1.1

0.082

CRP, mg/l

4.5 ± 2.1

5.5 ± 2.6

3.8 ± 1.2

0.399

3.3 ± 1.3

5.7 ± 1.4

6.0 ± 1.7

0.154

CRP > 3 mg/l, n (%)

9 (69.2)

25 (75.8)

4 (66.7)

0.723

14 (28.0)

59 (58.4)

10 (58.8)

0.001

TC, mg/dl

195.6 ± 33.5

211.1 ± 42.6

187.5 ± 23.1

0.301

195.1 ± 35.4

206.5 ± 43.2

207.8 ± 58.2

0.293

LDL-c, mg/dl

117.7 ± 25.5

137.6 ± 41.6

116.9 ± 19.8

0.202

122.2 ± 30.4

134.8 ± 41.7

132.4 ± 47.6

0.192

HDL-c, mg/dl

57.5 ± 15.3

53.3 ± 15.1

48.7 ± 11.6

0.509

51.4 ± 15.7

47.8 ± 13.3

50.8 ± 17.2

0.325

TG, mg/dl

109.8 ± 59.7

101.1 ± 42.6

109.5±41.5

0.682

105.3 ± 32.2

119.4 ± 36.6

130.4 ± 39.9

0.021

FPG, mg/dl

84.9 ± 11.9

93.2 ± 17.5

101.4 ± 48.9

0.340

104.3 ± 39.9

98.4 ± 29.1

116.7 ± 37.6

0.167

Creatinine, mg/dl

0.82 ± 0.23

1.30 ± 0.70

1.00 ± 0.20

0.564

0.90 ± 0.20

1.20 ± 0.60

1.10 ± 0.50

0.005

MDRD-eGFR, ml/min/1.73 m²

116.1 ± 31.5

91.1 ± 30. 1

98.3 ± 21.8

0.054

110.9 ± 33.3

86.9 ± 36.8

91.1 ± 48.9

0.001

Proteinuria, n (%)

3 (27.3)

11 (36.7)

2 (33.3)

0.133

14 (29.2)

37 (37.8)

7 (41.2)

0.510