Mean (SD)

Time

Period

RLAI N = 235

OA N = 70

P-Value (P?R Treatment Difference)

Retrospective (R)

Prospective (P)

P - R

P-Value

Retrospective (R)

Prospective (P)

P - R

P-Value

0 - 3 months

7.4 (12.3)

5.8 (11.7)

−1.6 (15.8)

0.12

3.7 (8.0)

6.1 (9.9)

2.4 (12.1)

0.10

NA

0 - 6 months

10.5 (18.6)

7.4 (15.0)

−3.1 (22.0)

0.032

5.0 (10.4)

7.1 (11.0)

2.1 (13.5)

0.19

NA

0 - 12 months

15.9 (30.5)

9.6 (21.9)

−6.3 (35.5)

0.007

7.3 (12.9)

7.4 (11.0)

0.1 (15.9)

0.95

0.0035

0 - 18 months

20.0 (34.4)

10.8 (29.8)

−9.2(43.4)

0.001

10.8 (16.9)

7.6 (11.0)

−3.2 (18.3)

0.15

NA

0 - 24 months

24.1 (38.4)

11.5 (32.3)

−12.6 (46.7)

<0.001

14.9 (21.3)

7.6 (11.0)

−7.3 (22.5)

0.009

0.0886

3 - 24 months

16.7 (31.6)

5.7 (29.2)

−11.0 (41.0)

<0.001

11.1 (19.0)

1.5 (5.5)

−9.7 (19.2)

<0.001

NA