Ethanol | TNBS | Oxazolone | ||||
6 hpi | 72 hpi | 6 hpi | 72 hpi | 6 hpi | 72 hpi | |
IL-1β | 1.2 ± 0.2 | −1.2 ± 0.2 | 7.2 ± 15.5* | 10.9 ± 12.7** | 2.9 ± 3.2* | 9.1 ± 8.4** |
IL-4/13a | 1.5 ± 0.3 | −2.2 ± 0.2* | −1.9 ± 0.6 | −2.6 ± 0.3* | −1.5 ± 0.4 | −3.1 ± 0.1** |
IL-4/13b | 2.3 ± 0.8 | 1.1 ± 0.3 | −1.2 ± 0.2 | 2.0 ± 0.3* | −1.0 ± 0.5 | 4.0 ± 1.5** |
IL-6 | NA | NA | NA | NA | NA | NA |
IL-8 | −1.4 ± 0.2 | 1.2 ± 0.7 | 1.2 ± 0.9 | 4.4 ± 3.8* | 1.3 ± 1.2 | 13.8 ± 27.7** |
IL-10 | 1.4 ± 0.4 | 2.1 ± 0.7* | 1.5 ± 0.6 | 3.3 ± 0.7** | 2.3 ± 0.9 | 1.7 ± 0.9 |
IL-12 | 1.8 ± 0.4 | 1.7 ± 1.1 | 1.4 ± 2.0 | 1.2 ± 0.5 | 1.2 ± 0.6 | 1.1 ± 0.8 |
IL-17A1 | 1.3 ± 0.3 | −1.3 ± 0.1 | −1.4 ± 0.2 | 1.7 ± 0.3 | 2.4 ± 0.7** | −3.6 ± 0.1** |
IL-17A2 | 1.7 ± 2.0 | 4.0 ± 13.6* | −1.1 ± 14.3 | −1.5 ± 0.3 | −6.2 ± 0.3 | 3.6 ± 9.7 |
IL-17A3 | 1.1 ± 0.3 | 1.1 ± 0.6 | −6.6 ± 0.2* | 1.3 ± 0.4 | 1.1 ± 0.7 | −1.4 ± 0.7 |
IL-22 | 2.0 ± 0.2 | 1.0 ± 0.5 | 1.7 ± 1.2 | 2.7 ± 0.8** | −1.4 ± 0.8 | 1.3 ± 1.3 |
IL-23 | NA | NA | NA | NA | NA | NA |
IFN-g | 2.4 ± 0.8* | 1.1 ± 0.2 | 1.5 ± 0.8 | 1.8 ± 0.4 | −1.4 ± 0.1 | 1.8 ± 0.7 |
TNF-α | 1.7 ± 0.6 | −1.2 ± 0.4 | 2.1 ± 0.7* | 2.3 ± 1.0* | 2.6 ± 1.1* | 4.8 ± 8.8* |
TGF-β | −1.2 ± 0.1 | −1.2 ± 0.1 | 1.2 ± 0.4 | 2.3 ± 0.3** | 1.2 ± 0.1 | 2.4 ± 0.4** |
mmp9 | −1.4 ± 0.5 | −1.4 ± 0.2 | 3.3 ± 1.5* | 19.8 ± 40.0** | 3.2 ± 0.4** | 29.2 ± 46.2** |
IgM | 1.3 ± 0.4 | −2.8 ± 0.5* | −1.4 ± 0.3 | −1.6 ± 0.5 | 1.2 ± 0.4 | 1.2 ± 0.3 |
IgZ | 2.0 ± 0.4 | 1.2 ± 0.5 | 2.5 ± 1.0 | 2.4 ± 0.7 | 4.1 ± 0.4 | −1.9 ± 0.7 |
CD4 | 1.9 ± 0.4 | 1.0 ± 0.2 | −1.3 ± 0.2 | −1.6 ± 0.3 | 1.4 ± 0.2 | −1.3 ± 0.2 |
CD8 | −3.7 ± 0.6 | −3.3 ± 1.5 | −3.0 ± 0.4 | −3.0 ± 0.9 | −1.0 ± 1.7 | −1.4 ± 0.7 |
C3 | −1.3 ± 0.2 | −1.2 ± 0.2 | −2.4 ± 0.2* | 6.4 ± 2.2** | −2.4 ± 0.2 | 3.4 ± 1.3* |
CRP | −1.3 ± 3.2 | −1.3 ± 0.4 | 2.9 ± 10.0 | 37.6 ± 22.0** | −2.6 ± 0.6 | 25.8 ± 9.8** |
SAA | 1.2 ± 0.4 | 1.4 ± 0.5 | 4.3 ± 61.3 | 142.0 ± 182.8** | 1.7 ± 2.1 | 175.9 ± 415.5** |
TLR-2 | 1.9 ± 0.6 | −1.4 ± 0.2 | −1.9 ± 0.3 | 1.2 ± 0.5 | −1.0 ± 0.5 | −2.9 ± 0.1** |
TLR-3 | 1.5 ± 0.5 | −1.2 ± 0.1 | −1.6 ± 0.2 | 1.4 ± 0.2 | −1.9 ± 0.1 | −1.6 ± 0.2 |
TICAM-1 | −1.3 ± 0.4 | 1.6 ± 1.2 | 3.0 ± 0.6* | 1.3 ± 1.2 | 2.2 ± 0.8 | 1.6 ± 1.0 |
MyD88 | 1.1 ± 0.3 | −1.1 ± 0.1 | −1.2 ± 0.2 | 1.3 ± 0.3 | 1.7 ± 0.3 | 1.8 ± 0.5 |
Foxp3 | 2.4 ± 0.7 | 1.4 ± 0.5 | 3.4 ± 2.4* | −1.2 ± 0.3 | 4.0 ± 12.4* | 1.6 ± 0.5 |
GATA-3 | 1.1 ± 0.3 | −1.5 ± 0.2 | −1.4 ± 0.2 | −1.1 ± 0.1 | 1.5 ± 0.4 | −1.5 ± 0.2 |
NF-κb | 1.0 ± 0.2 | −1.1 ± 0.1 | −1.3 ± 0.2 | 1.3 ± 0.2 | −1.8 ± 0.2 | 1.2 ± 0.3 |
STAT-3 | 1.1 ± 0.2 | −1.4 ± 0.1 | −1.1 ± 0.2 | 1.4 ± 0.6 | 1.1 ± 0.5 | 1.7 ± 0.3 |
STAT-4 | 1.4 ± 0.1 | 1.1 ± 0.1 | −1.3 ± 0.3 | 1.1 ± 0.3 | −1.3 ± 0.1 | 1.1 ± 0.2 |
STAT-6 | 1.3 ± 0.2 | −1.6 ± 0.1 | −1.0 ± 0.1 | 1.3 ± 0.3 | 1.1 ± 0.1 | −1.0 ± 0.2 |
T-bet | 3.6 ± 0.6* | −2.1 ± 0.1* | −1.0 ± 0.3 | −1.0 ± 0.1 | 2.1 ± 0.6 | −2.1 ± 0.3 |
S100A1 | 2.1 ± 0.3* | −1.2 ± 0.2 | 3.5 ± 1.4** | 3.7 ± 0.8** | 1.9 ± 0.3 | 4.2 ± 0.6** |