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| Studied metrics | ||
| Metric | Definition | Ranges | |
| 1 | LSI | Measures the complexity of the spot’s shape. | LSI ≥ 1 |
| 2 | MPS | Calculates the mean spot size in one category of spots | MPS > 0 |
| 3 | MPFD | Measures the mean fractal dimension of the spot. | 1 ≤ MPFD ≤ 2 |
| 4 | ED | Margin Congestion | ED > 0 |
| 5 | MSI | Mean Form Index Normalized by Area | MSI ≥ 1 |