|
| Cases (n = 221) | Controls (n = 179) | OR (95% CI)b | |
| % male | 83.3 | 79.3 |
|
|
| Age (yr), mean ± SD | 56.2 ± 6.4a | 57.9 ± 10.0 |
|
|
| Height (cm), mean ± SD | 164.6 ± 7.4 | 164.1 ± 8.0 |
|
|
| Weight (Kg), mean ± SD | 63.8 ± 9.7 | 66.1 ± 11.0 |
|
|
| BMI (Kg/m2), mean ± SD | 23.5 ± 2.6 | 24.5 ± 3.2 |
|
|
| Alcohol consumption |
|
|
|
|
| non-drinker, n (%) | 31 (14.0) | 62 (34.6) | 1 |
|
| light drinker, n (%) | 55 (24.9) | 37 (20.7) | 3.2 | 1.71 - 6.08 |
| moderate drinker, n (%) | 59 (26.7) | 41 (22.9) | 3.3 | 1.73 - 6.28 |
| heavy drinker, n (%) | 76 (34.4) | 39 (21.8) | 4.4 | 2.29 - 8.37 |
| Smoking status |
|
|
|
|
| never, n (%) | 58 (26.3) | 88 (49.2) | 1 |
|
| former, n (%) | 69 (31.2) | 41 (22.9) | 3.4 | 1.95 - 5.88 |
| current, n (%) | 94 (42.5) | 50 (27.9) | 3.3 | 1.82 - 5.86 |
| Genotype (n) |
|
|
|
|
| ADH1B |
|
|
|
|
| His/His (fast), n (%) | 137 (62.0) | 100 (55.9) | 1 |
|
| Arg/His (intermediate), n (%) | 74 (33.5) | 65 (36.3) | 0.8 | 0.55 - 1.28 |
| Arg/Arg (slow), n (%) | 10 (4.5) | 14 (7.8) | 0.5 | 0.22 - 1.23 |
| ALDH2 |
|
|
|
|
| Glu/Glu (high), n (%) | 141 (63.8) | 105 (58.7) | 1 |
|
| Glu/Lys (intermediate | 70 (31.7) | 59 (33.0) | 0.9 | 0.58 - 1.39 |
| Lys/Lys (low), n (%) | 10 (4.5) | 15 (8.3) | 0.5 | 0.22 - 1.18 |