| Adverse eventb | Patients, n (%) (N = 157) |
| All | 100 (63.7) |
| Gastrointestinal | 65 (41.4) |
| Diarrhea | 30 (19.1) |
| Nausea | 9 (5.7) |
| Colitis | 8 (5.1) |
| Skin | 44 (28.0) |
| Rash | 28 (17.8) |
| Neurological | 14 (8.9) |
| Endocrine | 6 (3.8) |
| Liver | 3 (1.9) |
| Serious adverse events | 46 (29.5) |
| Adverse event leading to discontinuation | 28 (17.8) |