Rats | Cough Reflexes/5min | ||||||
Control | 10 mg/kg | 20 mg/kg | 50 mg/kg | 100 mg/kg | 200 mg/kg | 300 mg/kg | |
Female | 210 ± 23 | 234 ± 24 | 202 ± 28 | 186 ± 60 | 167 ± 6 | 165 ± 11 | 142 ± 13** |
Male | 227 ± 25 | 206 ± 31 | 210 ± 22 | 196 ± 18 | 146 ± 11 | 167 ± 5* | 133 ± 19*** |