45 - 64 years; all participants | 45 - 64 years; with underlying disease | 45 - 64 years; without underlying disease | ||||||||||
The mean follow-up period (year) | 9.87 | 8.87 | 10.78 | |||||||||
The mean follow-up period until death | 11.51 | 11.02 | 12.38 | |||||||||
All participants/ death (N) | 23,730/3556 | 11,338/2281 | 12,392/1275 | |||||||||
n | No. of deaths | HR | 95% CI | n | No. of deaths | HR | 95% CI | n | No. of deaths | HR | 95% CI | |
BMI category | ||||||||||||
-18.5 | 255 | 74 | 2.69 | (2.09 - 3.40)* | 110 | 46 | 2.94 | (2.13 - 3.97)* | 145 | 28 | 2.44 | (1.61 - 3.55)* |
18.5 - 22.5 | 2982 | 473 | 1.20 | (1.06 - 1.36)* | 899 | 240 | 1.25 | (1.05 - 1.47)* | 2083 | 233 | 1.28 | (1.07 - 1.52)* |
22.5 - 25 | 4075 | 597 | 1.00 | (ref) | 1470 | 332 | 1.00 | (ref) | 2605 | 265 | 1.00 | (ref) |
25 - 30 | 9282 | 1408 | 1.02 | (0.92 - 1.12) | 4286 | 894 | 0.89 | (0.79 - 1.02) | 4996 | 514 | 1.00 | (0.86 - 1.16) |
30 - 35 | 4532 | 615 | 1.10 | (0.98 - 1.23) | 2687 | 447 | 0.87 | (0.75 - 1.00) | 1845 | 168 | 1.06 | (0.87 - 1.29) |
35- | 2604 | 389 | 1.75 | (1.54 - 1.99)* | 1886 | 322 | 1.26 | (1.08 - 1.47)* | 718 | 67 | 1.57 | (1.19 - 2.04)* |