| Name | Localization | |
| Class I | ||
| KDAC1 | Nucleus | |
| KDAC2 | Nucleus | |
| KDAC3 | Nucleus/cytoplasm | |
| KDAC8 | Cytoplasm | |
| Class II a | ||
| KDAC4 | Cytoplasm Nucleus | |
| KDAC5 | Cytoplasm Nucleus | |
| KDAC7 | Cytoplasm Mitochondria Nucleus | |
| KDAC9 | Cytoplasm Nucleus | |
| Class II b | ||
| KDAC6 | Cytoplasm | |
| KDAC10 | Cytoplasm Nucleus | |
| Class III (Sirtuins) (kDa) | ||
| Sirt1 | 120 | Cytoplasm Nucleus |
| Sirt2 | 43 | Cytoplasm Nucleus |
| Sirt3 | 28/44 (L) | Mitochondria Nucleus |
| Sirt4 | 35 | Mitochondria |
| Sirt5 | 34 | Mitochondria |
| Sirt6 | 37 | Nucleus |
| Sirt7 | 45 | Nucleus |
| Class IV | ||
| KDAC11 | Nucleus | |