Entry | X (amine) R | Y | Yield (%) | Reaction time (sec) | Melting points (˚C) | |
obs | lit | |||||
1 | H | H | 78 | 60 | 173 - 174 | 172 - 174 [21] |
2 | H | 4-OCH3 | 81 | 60 | 160 - 61 | 157 - 59 [21] |
3 | H | 4-NO2 | 70 | 60 | 199 | 196 - 98 [27] |
4 | H | 4-CH3 | 72 | 60 | 157 | 153 - 155 [27] |
5 | 2-Cl | H | 68 | 60 | 146 | 142 - 143 [23] |
6 | 3-Cl | H | 78 | 60 | 157 - 58 | 158 [23] |
7 | 4-Br | H | 67 | 60 | 190 - 91 | 189 - 190 [23] |
8 | 4-Cl | H | 65 | 60 | 120 - 121 | 119 [23] |
9 | 4-NO2 | H | 81 | 60 | 232 - 234 | 234 - 235 [30] |
10 | 3-NO2 | H | 72 | 60 | 179 | 176 [30] |
11 | 2-NO2 | H | 80 | 60 | 175 | 174 - 175 [30] |
12 | 2,4-diCl | H | 81 | 60 | 201 | 205 [30] |
13 | 4-CH3CO | H | 72 | 60 | 214 - 15 | 214 - 216 [30] |
14 | 4-CH3 | H | 65 | 60 | 156 | 153 - 154 [30] |
15 | 4-Cl | 4-CH3 | 77 | 60 | 177 - 79 | 179 - 183 [30] |
16 | 4-Cl | 2-CH3O | 82 | 60 | 180 - 182 | 180 - 181 [29] |
17 | 4-CH3O | 2-Cl | 65 | 60 | 203 - 205 | 203 - 206 [30] |
18 | 4-CH3 | 4-NO2 | 71 | 60 | 188 - 190 | 188 - 190 [30] |
19 | 4-NO2 | 4-NO2 | 78 | 60 | 208 - 211 | 209 [30] |