NATIONAL GUIDELINES

2010

2014

Pre-ART test

HIV Presumptive clinical signs

Positive serological test after 18 months

or positive PCR under 18 months

CD4 rate, hemogram, transaminases (ALAT)

HIV Presumptive clinical signs

Positive serological test after 18 months

or positive PCR,

CD4 rate, hemogram, transaminases (ALAT)

ART

eligibilitycriteria

WHO stage III or IV OMS

Under 5 years

Treat all

CD4 rate < 20%

after 5 years

WHO Stage III or IV

Or CD4 rate < 350 cell/mm3

First-line regimens

Mother receiving NVP in PMTCT

d4T/3TC/NVP

AZT/3TC + EFV

Under 3 years

ABC/3TC + LOP/r siâge 3 ans

Puis en 2011

AZT/3TC/NVP

From 3 to 10 years

ABC/3TC + EFV si 3 - 9 ans

Mother receiving not NVP in PMTCT

ABC/3TC + Lop/r

Up to 10 years

TDF/3TC/EFV si plus de 10 ans

Second-line regimens

AZT/3TC + NFV

ABC/3TC + LOP/r

ABC/3TC + LOP/r