Reaction No.

Cosolvent

% Cosolvent

kobs (h−1)

1

In the absence of cosolvent

0

0.17 ± 0.02

2

Ethylene Glycol (EG)

2

0.32 ± 0.03

3

Ethylene Glycol (EG)

5

0.53 ± 0.02

4

Ethylene Glycol (EG)

10

0.50 ± 0.04

5

Ethylene Glycol (EG)

20

0.48 ± 0.04

6

Dimethylsulfoxide (DMSO)

2

0.41 ± 0.04

7

Dimethylsulfoxide (DMSO)

5

0.69 ± 0.03

8

Dimethylsulfoxide (DMSO)

10

0.82 ± 0.07

9

Dimethylsulfoxide (DMSO)

20

0.73 ± 0.06

10

Acetonitrile (AN)

2

0.29 ± 0.03

11

Acetonitrile (AN)

5

0.54 ± 0.03

12

Acetonitrile (AN)

10

0.46 ± 0.02

13

Dimethylformamide (DMF)

2

0.31 ± 0.05

14

Dimethylformamide (DMF)

5

0.57 ± 0.05

15

Dimethylformamide (DMF)

10

0.74 ± 0.05

16

Dimethylformamide (DMF)

20

0.87 ± 0.07

17

Dimethylformamide (DMF)

30

0.75 ± 0.04