Reaction No. | Cosolvent | % Cosolvent | kobs (h−1) |
1 | In the absence of cosolvent | 0 | 0.17 ± 0.02 |
2 | Ethylene Glycol (EG) | 2 | 0.32 ± 0.03 |
3 | Ethylene Glycol (EG) | 5 | 0.53 ± 0.02 |
4 | Ethylene Glycol (EG) | 10 | 0.50 ± 0.04 |
5 | Ethylene Glycol (EG) | 20 | 0.48 ± 0.04 |
6 | Dimethylsulfoxide (DMSO) | 2 | 0.41 ± 0.04 |
7 | Dimethylsulfoxide (DMSO) | 5 | 0.69 ± 0.03 |
8 | Dimethylsulfoxide (DMSO) | 10 | 0.82 ± 0.07 |
9 | Dimethylsulfoxide (DMSO) | 20 | 0.73 ± 0.06 |
10 | Acetonitrile (AN) | 2 | 0.29 ± 0.03 |
11 | Acetonitrile (AN) | 5 | 0.54 ± 0.03 |
12 | Acetonitrile (AN) | 10 | 0.46 ± 0.02 |
13 | Dimethylformamide (DMF) | 2 | 0.31 ± 0.05 |
14 | Dimethylformamide (DMF) | 5 | 0.57 ± 0.05 |
15 | Dimethylformamide (DMF) | 10 | 0.74 ± 0.05 |
16 | Dimethylformamide (DMF) | 20 | 0.87 ± 0.07 |
17 | Dimethylformamide (DMF) | 30 | 0.75 ± 0.04 |