Treatment

Dose (mg/kg)

Onset of action (min)

Duration of sleeping time (min)

Control

0.1 ml/mouse

14.47 ± 0.41

97.00 ± 1.09

Diazepam

1

7.64 ± 0.07***

186.80 ± 0.91***

METE

200

11.50 ± 0.68***

132.00 ± 1.94***

METE

400

8.50 ± 0.22***

177.60 ± 1.24***