| Demographics | IPF cases | Pre-operative day-case controls |
| No of cases | 149 | 448 |
| % male | 52 | 58 |
| Mean age and range | 72 (41 - 92) | 73 (40 - 80) |
| Caucasian | 81% | 75% |
| Smoking status | 90% ex-smoker | Non-smoker or <10 pack years |
| Chest X ray | Abnormal | normal |
| Normal ECG | Variable | 100% |
| Past cardiorespiratory disease | Yes | None |
| Diabetes | 33% | None |
| Alcohol intake units/week | 0 - 6 | 0 - 1 |
| Age match 35 - 40 yrs 45 - 54 yrs 55 - 64 yrs 65 - 75 yrs 75 yrs+ | Number of cases-149 2 10 20 40 77 | Number of cases-448 40 70 106 110 122 |
| Criteria for IPF cases (major and minor criteria) as per ATS/ERS criteria | Insidious onset Bibasilar inspiratory crackles Progressive dyspnoea Duration > 3 months CT consistent with UIP/NSIP or mixed ± lung biopsy Restrictive pulmonary function of reduced VC, FVC, TLCO, KCO Exclusion of other causes of interstitial lung disease |
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