HE | aMCI | AD |
・ CDR = 0 ・ MMSE ≥ 28 ・ GDS < 20 ・ TICS-M total score ≥ 29 ・ TICS-m WLR ≥ 11 ・ No significant SMC ・ Without evidence of depression ・ Without dementia of ADL impairment | ・ CDR ≤ 0.5 ・ MMSE ≥ 23 ・ GDS < 20 ・ TICS-M total score < 29 and > 14 ・ TICS-m WLR < 10 ・ Without dementia and with minimal or no ADL impairment ・ Met Petersen criteria including the presence of SMC | ・ CDR > 0.5 ・ MMSE ≥ 16 ・ GDS < 20 ・ TICS-M total score < 29 and > 14 ・ TICS-m WLR < 10 ・ Possible or probable AD according to previous or new clinical diagnosis using the NINCDS-ADRDA criteria |