| Antibiotic | Growth Condition1 | MIC (μg/ml) | MBC (μg/ml) | Biofilm (No. of Isolates Affected) | Peak Biofilm Level Abs5402 | Drug Concentration (µg/ml) at Peak Biofilm Level3 (Maximum Drug Concentration Affecting Biofilm) | Ratio (Test Biofilm Level /Control Biofilm Level)5 |
| Amoxicillin- clavulanate6 |
|
|
|
|
|
|
|
|
| Aero | 0.125 - 2.0 | 0.125 - 2.0 | 0 | NE4 | NE | NE |
|
| CO2 | 0.125 - 2.0 | 0.125 - 2.0 | 0 | NE | NE | NE |
|
| Anaero | 0.032 - 1.0 | 0.063 - 1.0 | 0 | NE | NE | NE |
| Cefaclor7 |
|
|
|
|
|
|
|
|
| Aero | 16.0 - 256.0 | 16.0 - 256.0 | 0 | NE | NE | NE |
|
| CO2 | 4.0 - 64.0 | 4.0 - 128.0 | 0 | NE | NE | NE |
|
| Anaero | 0.063 - 32.0 | 1.0 - 32.0 | 0 | NE | NE | NE |
| Cefdinir7 |
|
|
|
|
|
|
|
|
| Aero | 0.5 - 8.0 | 0.5 - 16.0 | 0 | NE | NE | NE |
|
| CO2 | 0.5 - 4.0 | 1.0 - 4.0 | 0 | NE | NE | NE |
|
| Anaero | 0.008 - 1.0 | 0.25 - 1.0 | 0 | NE | NE | NE |
| Cefixime7 |
|
|
|
|
|
|
|
|
| Aero | 0.125 - 2.0 | 0.5 - 4.0 | 0 | NE | NE | NE |
|
| CO2 | 0.125 - 2.0 | 0.5 - 4.0 | 0 | NE | NE | NE |
|
| Anaero | 0.002 - 0.25 | 0.125 - 2.0 | 0 | NE | NE | NE |
| Ceftriaxone7 |
|
|
|
|
|
|
|
|
| Aero | 0.063 - 4.0 | 0.063 - 4.0 | 0 | NE | NE | NE |
|
| CO2 | 0.063 - 2.0 | 0.063 - 2.0 | 0 | NE | NE | NE |
|
| Anaero | 0.063 - 0.25 | 0.032 - 1.0 | 0 | NE | NE | NE |
| Cefuroxime7 |
|
|
|
|
|
|
|
|
| Aero | 2.0 - 16.0 | 2.0 - 16.0 | 0 | NE | NE | NE |
|
| CO2 | 2.0 - 16.0 | 2.0 - 16.0 | 0 | NE | NE | NE |
|
| Anaero | 0.5 - 8.0 | 0.032 - 1.0 | 0 | NE | NE | NE |
| Azithromycin8 |
|
|
|
|
|
|
|
|
| Aero | 0.063 - 0.5 | 0.125 - 1.0 | 0 | NE | NE | NE |
|
| CO2 | 0.25 - 1.0 | 1.0 - 2.0 | 1 | 0.38 ± 0.002 | 0.25 (0.25) | 2.21 |
|
| Anaero | 0.004 - 0.25 | 0.5 - 2.0 | 0 | NE | NE | NE |
| Clarithromycin8 |
|
|
|
|
|
|
|
|
| Aero | 0.5 - 4.0 | 0.5 - 8.0 | 0 | NE | NE | NE |
|
| CO2 | 0.5 - 4.0 | 0.5 - 4.0 | 0 | NE | NE | NE |
|
| Anaero | 0.016 - 0.016 | 0.5 - 4.0 | 0 | NE | NE | NE |