Virus | Genes and Proteins Involved in Cancer | Cancer | Treatment Available for Virus Infection |
EBV | LMP1, LMP2A, AKT, NF-kB, NOTCH, and phosphatidylinositol 3 kinase | Hodgkin Lymphoma, Burkitt Lymphoma, Diffuse Large B Cell Lymphoma, Pyrothorax Lymphoma, Nasopharyngeal Carcinoma, Gastric Carcinoma, and Leiomyosarcoma | No specific antiviral treatment |
HBV/HCV | TP53, CTNNB1, AXIN, ARID1A, AXIN1, and CDKN2A, and ARID1A | Hepatocellular carcinoma | Pegylated interferon, ribavirin, boceprevir, and telaprevir |
HHV-6 | ORF-1, p53, U95, NF-kB | Oral Squamous Cell Carcinoma, Hodgkin’s Disease, non-Hodgkin’s lymphoma, and cervical carcinoma | No specific antiviral treatment; immunotherapy |
HHV-8 | K1, vIRF, and cIL8R | Karposi’s Sarcoma and Primary Effusion Lymphoma | Ganciclovir and Foscarnet |
HPV | E5, E6, and E7 | Cervical Cancer | Vitamin A and curcumin |
HTLV-1 | p53 | Adult T-Cell Leukemia/Lymphoma | Corticosteroids, Plasmapheresis, Cyclophosphamide, Interferon, Valproic Acid, and Zidovudine |
MCPyV | CD3G, CD3D, ZAP70, and IGHM | Merkel Cell Carcinomas | Nospecific antiviral treatment |