Variable | Controls | Non-users | Intervention | p-value |
(n = 75) | (n = 70) | (n = 108) | ||
Age (years) | 56 (47 - 64) | 52 (39 - 62) | 53 (42 - 64) | p = 0.4 |
Male sex (%) | 56 | 59 | 56 | p = 0.9 |
Actual bodyweight (kg) | 85 (66 - 97) | 88 (64 - 107) | 78 (67 - 96) | p = 0.7 |
<60 kg | 13% | 20% | 10% | p = 0.2 |
60 - 80 kg | 25% | 20% | 46% | p < 0.005 |
81 - 100 kg | 40% | 29% | 21% | p = 0.02 |
>100 kg | 21% | 31% | 22% | p = 0.3 |
eGFR (ml/min/1.73 m2) | 89 (56 - 109) | 81 (54 - 114) | 70 (47 - 102) | p = 0.2 |
<15 or RRT | 12% | 24% | 15% | p = 0.1 |
15 - 49 | 19% | 11% | 19% | p = 0.4 |
50 - 90 | 32% | 24% | 39% | p = 0.1 |
>90 | 37% | 40% | 28% | p = 0.2 |
Vancomycin TDD (mg) | 2000 (2000 - 2250) | 2000 (1250 - 3000) | 2000 (1250 - 2500) | p = 0.5 |