Authors, place and year of study, sample size

Frequency of bone fragility (osteopenia and/or osteoporosis)

Factors associated with bone fragility

Gabriel bandzanni and al, Brésil, 2011, n = 65

81.5% (57 % ostéopénia and 24.5% ostéoporosis)

Low GFR, severe anaemia with p = 0.02, low BMI with p = 0.17

Mona Sarrai and al, 2007, NY, USA, n = 103

79.6%

Homozygous phenotype with p = 0.018; Severe anaemia with p < 0.0001, High ferritinaemia with p = 0.010, Low BMI with p = 0.003

Redonda G Miller and al, JH, 2006, USA, n = 32

72%

BMI with p = 0.007, sex M with p = 0.02, homozygous phenotype SS