Accelerated Phase | Blast Phase | ||
WHO | ELN | WHO | ELN |
1) Spleen Persistent or increasing splenomegaly unresponsive to treatment | / | / | / |
2) WBC Persistent or increasing WBC (>10 × 109/L) unresponsive to treatment | / | / | / |
3) Blast cells 10% to 19% | 15 to 29% | >20% | >30% |
4) Basophils > 20% | >20% | / | / |
5) Platelets Count > 1000 × 109/l uncontrolled by therapy < 100 × 109/l unrelated to therapy | / | / | / |
yes | / | / | |
6) CCA/Ph+ Present | Present | / | / |
7) Extramedullary/Involvement | / | Present | Present |