Accelerated Phase

Blast Phase

WHO

ELN

WHO

ELN

1) Spleen Persistent or increasing splenomegaly unresponsive to treatment

/

/

/

2) WBC Persistent or increasing WBC (>10 × 109/L) unresponsive to

treatment

/

/

/

3) Blast cells 10% to 19%

15 to 29%

>20%

>30%

4) Basophils > 20%

>20%

/

/

5) Platelets Count > 1000 × 109/l uncontrolled by therapy < 100 × 109/l unrelated to therapy

/

/

/

yes

/

/

6) CCA/Ph+ Present

Present

/

/

7) Extramedullary/Involvement

/

Present

Present