
No.	R₁	R₂	X	Formule	IC₅₀^a (nM)	Log P	N^o violation
1	H	H	H	C₁₄H₁₁N₃	344	3.14	0
2	H	H	F	C₁₄H₁₀FN₃	56	3.62	0
3	H	H	Cl	C₁₄H₁₀ClN₃	23	4.03	0
4	H	H	Br	C₁₄H₁₀BrN₃	27	4.34	0
5	H	H	I	C₁₄H₁₀IN₃	80	4.60	0
6	H	H	CF₃	C₁₅H₁₀F₃N₃	577	4.35	0
7	OMe	H	H	C₁₅H₁₃N₃O	55	3.05	0
8	OMe	H	H	C₁₅H₁₂BrN₃O	30	4.26	0
9	NH₂	H	H	C₁₄H₁₂N₄	770	1.86	0
10	NH₂	H	CF₃	C₁₅H₁₁F₃N₄	574	3.07	0
11	NH₂	H	Br	C₁₄H₁₁BrN₄	0.78	3.06	0
12	NO₂	H	H	C₁₄H₁₀N₄O₂₁₃	5000	2.87	0
13	NO₂	H	Br	C₁₄H₉BrN₄O₂	900	4.07	0
14	NO₂	H	CF₃	C₁₅H₉F₃N₄O₂	>10⁴	4.08	0
15	H	MeO	H	C₁₅H₁₃N₃O	120	3.05	0
16	H	MeO	Br	C₁₅H₁₂BrN₃O	10	4.26	0
17	H	NH₂	H	C₁₄H₁₂N₄	100	1.86	0
18	H	NH₂	F	C₁₄H₁₁FN₄	2.0	2.34	0
19	H	NH₂	Cl	C₁₄H₁₁ClN₄	0.25	2.75	0
20	H	NH₂	Br	C₁₄H₁₁BrN₄	0.1	3.06	0
21	H	NH₂	I	C₁₄H₁₁IN₄	0.35	3.32	0
22	H	NH₂	CF₃	C₁₅H₁₁F₃N₄	3.3	3.07	0
23	H	NO₂	H	C₁₄H₁₀N₄O₂	1.2 × 10⁴	2.87	0
24	H	NO₂	F	C₁₄H₉FN₄O₂	6100	3.35	0
25	H	NO₂	Cl	C₁₄H₉CIN₄O₂	810	3.76	0
26	H	NO₂	Br	C₁₄H₉BrN₄O₂	1000	4.07	0
27	H	NO₂	I	C₁₄H₉IN₄O₂	540	4.33	0
28	H	NO₂	CF₃	C₁₅H₉F₃N₄O₂	>10⁴	4.08	0
29	OMe	OMe	H	C₁₆H₁₅N₃O₂	29	2.87	0
30	OMe	OMe	F	C₁₆H₁₄FN₃O₂	3.8	3.36	0