Nominal concentration

Intra-dayprecision (n = 10)

CV (%)

Bias (%)

Inter-dayprecision (n = 15)

CV (%)

Bias (%)

(mg/l)

Mean measured concentration ± SD (mg/l)

Mean measured concentration ± SD (mg/l)

Piperacillin (228 nm)

30

26.18 ± 1.26

4.8

12.74

26.11 ± 1.08

4.14

12.96

50

48.61 ± 1.6

3.29

2.77

48.85 ± 1.44

2.94

2.31

200

187.51 ± 4.49

2.39

6.24

188.31 ± 4.33

2.3

5.84

400

367.05 ± 9.64

2.63

8.24

376.29 ± 13.07

3.47

5.93

Ciprofloxacin (280 nm)

0.5

0.5 ± 0.04

8.02

0.44

0.5 ± 0.04

8.99

0.6

1

1.04 ± 0.09

8.82

3.91

1.03 ± 0.09

8.49

2.95

4

3.98 ± 0.19

4.74

0.59

3.93 ± 0.18

4.47

1.7

8

7.94 ± 0.38

4.81

0.8

7.86 ± 0.35

4.4

1.75

Ciprofloxacin (315 nm)

0.5

0.5 ± 0.02

4.95

0.37

0.5 ± 0.03

5.05

0.96

1

1.04 ± 0.06

5.72

3.88

1.03 ± 0.05

5.1

3.04

4

4.08 ± 0.17

4.05

1.87

4.03 ± 0.18

4.41

0.69

8

8.11 ± 0.41

5.11

1.35

7.97 ± 0.43

5.37

0.43