Nominal concentration | Intra-dayprecision (n = 10) | CV (%) | Bias (%) | Inter-dayprecision (n = 15) | CV (%) | Bias (%) | |
(mg/l) | Mean measured concentration ± SD (mg/l) | Mean measured concentration ± SD (mg/l) | |||||
Piperacillin (228 nm) | |||||||
30 | 26.18 ± 1.26 | 4.8 | 12.74 | 26.11 ± 1.08 | 4.14 | 12.96 | |
50 | 48.61 ± 1.6 | 3.29 | 2.77 | 48.85 ± 1.44 | 2.94 | 2.31 | |
200 | 187.51 ± 4.49 | 2.39 | 6.24 | 188.31 ± 4.33 | 2.3 | 5.84 | |
400 | 367.05 ± 9.64 | 2.63 | 8.24 | 376.29 ± 13.07 | 3.47 | 5.93 | |
Ciprofloxacin (280 nm) | |||||||
0.5 | 0.5 ± 0.04 | 8.02 | 0.44 | 0.5 ± 0.04 | 8.99 | 0.6 | |
1 | 1.04 ± 0.09 | 8.82 | 3.91 | 1.03 ± 0.09 | 8.49 | 2.95 | |
4 | 3.98 ± 0.19 | 4.74 | 0.59 | 3.93 ± 0.18 | 4.47 | 1.7 | |
8 | 7.94 ± 0.38 | 4.81 | 0.8 | 7.86 ± 0.35 | 4.4 | 1.75 | |
Ciprofloxacin (315 nm) | |||||||
0.5 | 0.5 ± 0.02 | 4.95 | 0.37 | 0.5 ± 0.03 | 5.05 | 0.96 | |
1 | 1.04 ± 0.06 | 5.72 | 3.88 | 1.03 ± 0.05 | 5.1 | 3.04 | |
4 | 4.08 ± 0.17 | 4.05 | 1.87 | 4.03 ± 0.18 | 4.41 | 0.69 | |
8 | 8.11 ± 0.41 | 5.11 | 1.35 | 7.97 ± 0.43 | 5.37 | 0.43 |