DNA Probe: |
ACTB―most abundant proteins in eukaryotic cells and are involved in cell motility, structure, and integrity. Negative control. |
DEFB1―an antimicrobial peptide implicated in the resistance of epithelial surfaces to microbial colonization. |
IFNG―an antimicrobial peptide implicated in the resistance of epithelial surfaces to microbial colonization. |
IL6―secreted by T cells and macrophages to stimulate immune response during infection and after trauma. |
CD160―expression is tightly associated with peripheral blood NK cells and CD8 T lymphocytes with cytolytic effector activity. |
DEFB119―antimicrobial peptide produced by neutrophils that protects tissues and organs from infection by a variety of microorganisms. |
IL10―a cytokine synthesis inhibitory factor, which is an anti-inflammatory cytokine. |
LAG3―inhibitory receptor expressed on activated CD8 and CD4 T cells (including Tregs) triggering signalling within Dendritic cells. |
CD19―expressed during all phases of B cell development until terminal differentiation into plasma cells. |
DEFB127―Defensins are cysteine-rich cationic polypeptides that are important in the immunologic response to invading microorganisms. |
IL12A―acts on T and natural killer cells and has a broad array of biological activities. |
NFKB1―involved in the regulation of genes that impact not only immune responses but also cell proliferation, survival, and differentiation. |
CD4―co-receptor of the T cell receptor (TCR) and assists the latter in communicating with antigen-presenting cells. |
EGF―Epidermal growth factor is a growth factor that stimulates cell growth, proliferation, and differentiation by its receptor EGFR. |
IL12B―expressed by activated macrophages, essential inducer of Th1 cells development for protection to intracellar pathogens. |
PDCD1―Programmed Cell Death Protein 1, part of the immunoglobulin superfamily and is expressed on T cells and pro-B cells. |
CD40―expressed on activated T cells, part of the TNF superfamily of molecules on antigen-presenting cells (APC). |
GAPDH―Glyceraldehyde 3-phosphate dehydrogenase catalase the sixth step of glycolysis, initiation of apoptosis, ER to Golgi shuttling. |
IL18―proinflammatory cytokine that belongs to the IL-1 superfamily, produced by macrophages and other cells. |
TGFA―TGF-α can be produced in macrophages, brain cells, and keratinocytes. TGF-α induces epithelial development. |
CD8A―found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. |
HBD―Haemoglobin subunit delta is a protein that in humans. Negative control. |
IL2―promotes the differentiation of T cells into effector T cells and into memory T cells helping the body fight off infections. |
CD8B―found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. |
IFNA1―produced by macrophages and has antiviral activity. |
IL4―cytokine that induces differentiation of naive helper T cells (Th0 cells) to Th2 cells. |
DEFA1―antimicrobial and cytotoxic peptides thought to be involved in host defense. |
IFNB1―antiviral, antibacterial, and anticancer properties. |
IL5―cytokine that acts as a growth and differentiation factor for both B cells and eosinophils. |