| Studies Characteristics | |||||
| Author | Year | Methods | Country | Sample (n) | H186R frequency |
| Walsh et al., [32] | 2009 | gDNA real-time PCR | Uganda | 160 | 0.108 |
| Walsh et al., [32] | 2009 | gDNA real-time PCR | Tanzania | 174 | 0.148 |
| Reddy et al., [13] | 2010 | TaqMan & PCR-RFLP | South Africa | 250 | 0.307 |
| Zhao et al., [31] | 2012 | Sequencing | Central African Republic | 24 | 0.14 |
| Zhao et al., [31] | 2012 | Sequencing | Democratic Republic of Congo | 24 | 0.35 |
| Compaore et al., [24] | 2016 | Real-time PCR (Taqman) | Burkina Faso | 708 | 0.44 |
| Mhandire et al., [29] | 2016 | PCR-RFLP | Zimbabwe | 104 | 0.40 |
| Compaore et al., [25] | 2016 | Real time PCR (Taqman) | Burkina Faso | 274 | 0.47 |
| Matume et al., [28] | 2019 | NGS | South Africa | 165 | 0.37 |