| Algae Mask | Untreated area | ||
t0 n = 22 | t1 n = 22 | t0 n = 20 | t1 n = 20 | |
TEWL mean values | 6.07 | 9.28 | 6.14 | 8.52 |
± SD | 1.78 | 2.29 | 1.40 | 1.73 |
| t1 - t0 n = 20 | t1 - t0 n = 20 | ||
Mean differences | 2.85 | 2.30 | ||
± SD | 2.08 | 1.81 | ||
Mean differences (%) | 53.70% | 41.32% | ||
± SD (%) | 47.76% | 31.01% | ||
No. of subjects with TEWL decrease | 2 | 3 | ||
% of subjects with TEWL decrease | 10.00% | 15.00% | ||
Maximum decrease (%) | −11.60% | −23.90% | ||
Mean decrease among subjects with positive effects (%) | −9.40% | −9.89% | ||
p value (before vs after product’s application) | <0.001* | <0.001* | ||
p value (Investigational product vs untreated area) | 0.323* | − |