Isotretinoin therapy

Placebo therapy

Before

therapy

Day 14

One month

Two

months

Three

months

Four

months

Five

months

Six months

Mean

13.133

10.567

7.6

5.5667

4.0667

5.9333

8.2

10.667

SD

2.556

3.9277

4.9522

5.3219

4.2421

4.7119

4.3263

3.8714

P-value

0.103

NS

0.023

S

P < 0.001

HS

P < 0.001

HS

P < 0.001

HS

0.046

S

0.107

NS