| P value | AG2* (n = 292) | AG1* (n = 140) |
|
| 1.0 | 80 ± 13.3 | 80 ± 12.9 | Age (years) |
| 0.8 | 188 (64) | 53 (66) | Female sex |
| 0.6 | 67 ± 3 | 67 ± 2 | Body weight (kg) |
| 0.002 | 11 ± 10 | 15 ± 18 | Days of hospitalization |
| Indication for treatment with amikacin** | |||
| 1.0 | 39 (13) | 18 (13) | Presence of sepsis |
| 0.6 | 254 (87) | 125 (90) | Urinary tract infection |
| 0.7 | 21 (7) | 8 (6) | Bacteremia |
| 0.02 | 49 (17) | 39 (28) | Pneumonia |
| 0.9 | 52 (18) | 27 (19) | Other infections diseases1 |
| 0.3 | 1.3 ± 0.5 | 1.3 ± 0.6 | Total number indications for treatment with amikacin per one patient |
| Concomitant comorbidities** | |||
| 0.9 | 2.0 ± 1.7 | 2.0 ± 1.8 | Total number of other active disease during hospitalization per one patient2 |
| 1.0 | 8.6 ± 5.1 | 8.6 ± 4.4 | Total number of chronic disease per one patient |
| 0.7 | 7.2 ± 4.3 | 7.0 ± 3.2 | Total number of chronic medications and others per one patient |
| 0.6 | 11.4 ± 5.6 | 11.1 ± 5.1 | Total number of medications and others during hospitalization per one patient3 |
| 1 | 5.9 ± 2.6 | 5.9 ± 2.6 | Charlson Comorbidity Index |
| 0.7 | 8.2 ± 4.4 | 7.9 ± 4.5 | Chronic Disease Score |
| 0.6 | 33 (11) | 19 (14) | Death during hospitalization |
| Acute renal failure (ARF) per study definitions | |||
| 0.7 | 105 (39) | 53 (41) | Unstable renal function4 |
| 0.8 | 40 (15) | 18 (14) | ARF per Creatinine calculation5 |
| 0.9 | 39 (14) | 19 (15) | ARF per MDRD equation6 |
| 0.9 | 37 (14) | 18 (14) | ARF per Cockroft\Gaul equation6 |
| 0.9 | 36 (13) | 18 (14) | ARF per CKD-EPI equation6 |