Genotypic and allelic frequencies in cirrhosis and HCC

MAP3K14

(rs2074292)

Cirrhosis

N = 16 (%)

HCC

N = 48 (%)

OR (95% CI)

p-Value

Genotypes

AA

2 (12.5)

5 (10.41)

Reference

AG

11 (68.75)

41 (85.41)

1.49 (0.25 - 8.75)

1

GG

3 (18.75)

2 (4.16)

0.26 (0.02 - 3.02)

0.62

Alleles

A

15 (46.87)

51 (53.13)

Reference

G

17 (53.13)

45 (46.87)

0.77 (0.34 - 1.73)

0.68

CD40

(rs1883832)

Cirrhosis

N = 15 (%)

HCC

N = 46 (%)

OR (95% CI)

p-Value

Genotypes

CC

8 (53.3)

28 (60.9)

Reference

CT

7 (46.7)

15 (32.6)

0.61 (0.18 - 2.01)

0.61

TT

0

3 (6.5)

NA

0.86

Alleles

C

23 (76.7)

71 (77.2)

Reference

T

7 (23.3)

21 (22.8)

0.97 (0.36 - 2.57)

1

Genotypic and allelic frequencies in cirrhosis and controls

MAP3K14

(rs2074292)

Cirrhosis

N = 16 (%)

Controls

N = 90 (%)

OR (95% CI)

p-Value

Genotypes

AA

2 (12.5)

7 (7.77)

Reference

AG

11 (68.75)

78 (86.66)

0.49 (0.09 - 2.68)

0.75

GG

3 (18.75)

5 (55.55)

2.1 (0.25 - 17.59)

0.87

Alleles

A

15 (46.87)

92 (51.1)

Reference

G

17 (53.13)

88 (48.9)

1.18 (0.55 - 2.51)

0.8

CD40

(rs1883832)

Cirrhosis

N = 15 (%)

Controls

N = 53 (%)

OR (95% CI)

p-Value

Genotypes

CC

8 (53.3)

25 (47.2)

Reference

CT

7 (46.7)

7 (13.2)

3.12 (0.83 - 11.64)

0.16

TT

0

21 (39.6)

0 (NA)

0.04

Alleles

C

23 (76.7)

57 (53.7)

Reference

T

7 (23.3)

49 (46.3)

0.35 (0.13 - 0.89)

0.04

Genotypic and allelic frequencies in HCC and Controls

MAP3K14

(rs2074292)

HCC

N = 48 (%)

Controls

N = 90 (%)

OR (95% CI)

p-Value

Genotypes

AA

5 (10.41)

7 (7.77)

Reference

AG

41 (85.41)

78 (86.66)

0.73 (0.21 - 2.46)

0.85

GG

2 (4.16)

5 (55.55)

0.56 (0.07 - 4.14)

0.93

Alleles

A

51 (53.13)

92 (51.1)

Reference

G

45 (46.87)

88 (48.9)

0.92 (0.56 - 1.51)

0.84