Genotypic and allelic frequencies in CHB and cirrhosis | ||||||
MAP3K14 (rs2074292) |
|
| CHB N = 69 (%) | Cirrhosis N = 16 (%) | OR (95% CI) | p-Value |
Genotypes | AA | 5 (7.25) | 2 (12.50) | Reference | ||
AG | 61 (88.41) | 11 (68.75) | 2.21 (0.38 - 12.90) | 0.71 | ||
GG | 3 (4.35) | 3 (18.75) | 0.40 (0.04 - 3.95) | 0.82 | ||
Alleles | A | 71 (51.45) | 15 (46.87) | Reference | ||
G | 67 (48.55) | 17 (53.13) | 1.2 (0.5 - 2.59) | 0.78 | ||
CD40 (rs1883832) |
|
| CHB N = 59 (%) | Cirrhosis N = 15 (%) | OR (95% CI) | p-Value |
Genotypes | CC | 57 (96.6) | 8 (53.3) | Reference | ||
CT | 1 (1.7) | 7 (46.7) | 49 (5.4 - 460.2) | <0.001 | ||
TT | 1 (1.7) | 0 | 0 (NA) | 1 | ||
Alleles
| C | 115 (97.5) | 23 (76.7) | Reference | ||
T | 3 (2.5) | 7 (23.3) | 11.66 (2.8 - 48.49) | <0.001 | ||
Genotypic and allelic frequencies in CHB and HCC | ||||||
MAP3K14 (rs2074292) |
|
| CHB N = 69 (%) | HCC N = 48 (%) | OR (95% CI) | p-Value |
Genotypes | AA | 5 (7.25) | 5 (10.42) | Reference | ||
AG | 61 (88.41) | 41 (85.42) | 1.48 (0.1 - 5.46) | 0.79 | ||
GG | 3 (4.35) | 2 (4.17) | 1.5 (0.17 - 13.25) | 1 | ||
Alleles | A | 71 (51.45) | 51 (53.13) | Reference | ||
G | 67 (48.55) | 45 (46.87) | 0.93 (0.5 - 1.57) | 0.9 | ||
CD40 (rs1883832) |
|
| CHB N = 59 (%) | HCC N = 46 (%) | OR (95% CI) | p-Value |
Genotypes | CC | 57 (96.6) | 28 (60.9) | Reference | ||
CT | 1 (1.7) | 15 (32.6) | 30.53 (3.83 - 243) | <0.001 | ||
TT | 1 (1.7) | 3 (6.5) | 6 (0.6 - 61.4) | 0.23 | ||
Alleles | C | 115 (97.5) | 71 (77.2) | Reference | ||
T | 3 (2.5) | 21 (22.8) | 11.33 (3.26 - 39.39) | < 0.001 | ||
Genotypic and allelic frequencies in CHB and Controls | ||||||
MAP3K14 (rs2074292) |
| CHB N = 69 (%) | Controls N = 90 (%) | OR (95% CI) | p-Value | |
Genotypes | AA | 5 (7.25) | 7 (7.78) | Reference | ||
AG | 61 (88.41) | 78 (86) | 1.09 (0.33 - 3.61) | 0.88 | ||
GG | 3 (4.35) | 5 (5.56) | 0.85 (0.3 - 5.26) | 0.85 | ||
Alleles | A | 71 (51.45) | 92 (51.1) | Reference | ||
G | 67 (48.55) | 88 (48.9) | 0.98 (0.63 - 1.53) | 1 |