Patients admitted with COVID-19 infection with chronic disease

(38.34%)

(Group A)

Patients admitted with COVID-19

infection without chronic disease

(74.66%)

(Group B)

p-Value

Average age at diagnosis

7.7 ± 5.6

10.5 ± 5.9

0.017

Gender (M %)

53%

45%

0.423

Symptomatic (n, %)

- Cough

15 (39.5)

17 (23.0)

0.070

- Fever

15 (39.5)

14 (18.9)

0.020

- Fatigue

10 (26.3)

8 (10.8)

0.037

- Nasal symptoms

5 (13.2)

12 (16.2)

0.676

- Dyspnea

9 (23.7)

6 (8.1)

0.024

- Headache

2 (5.3)

11 (14.9)

0.758

- Sore throat

1 (2.6)

11 (14.9)

0.049

- Vomiting

1 (2.6)

8 (10.8)

0.133

- Others (tachycardia, chest pain, unsteady gait)

3 (7.9)

5 (6.8)

0.831

- Muscle aches

5 (13.2)

3 (4.1)

0.080

- Tachypnea

3 (7.9)

4 (5.4)

0.606

- Abdominal pain

2 (5.3)

5 (6.8)

0.758

- Diarrhea

0

5 (6.8)

0.103

- Poor appetite

3 (7.9)

1 (1.3)

0.076

- Hypoactivity

2 (5.3)

0

0.048

- Loss of smell

0

0

- Loss of taste

0

0

Radiological evaluation:

- Abnormal CXR (n, %)

14 (36.8)

13 (17.6)

0.027

Laboratory evaluation:

- High inflammatory markers (ESR, CRP)

5 (13.2)

12 (16.2)

0.676

- Average LDH

560

417

- Average Ferritin

100

32.1

- Hb (Avg ± SD)

12.2 ± 1.80

12.6 ± 1.67

0.353

- WBC

8634.6 ± 5947.04

7622 ± 2972

0.327

- Lymphocyte count

3039.69 ± 3410.97

2447.84 ± 1234.4

0.286

- Neutrophilic count

4284.49 ± 3025.9

3820.3 ± 2138.27

0.454

- Platelet count

270,807 ± 202832.5

279145.8 ± 149500.4

0.844

Level of care:

- Floor

33 (86.8)

71 (95.9)

0.080

- ICU

5 (13.2)

3 (4.1)

0.080

Highest respiratory support:

- None

32 (84.2)

73 (98.6)

0.036

- CPAP

2 (5.3)

0

0.048

- HFNC

1 (2.6)

1 (1.4)

0.652

- Mechanical ventilation

3 (7.9)

0

0.016

COVID-19 specific treatment:

- Hydroxychloroquine

1 (2.6)

8 (10.8)

0.133

- Steroids

5 (13.2)

3 (4.1)

0.080

- IVIG

1 (2.6)

1 (1.4)

0.653

- Remdesivir

0

1 (1.4)

0.465

- Azithromycin

1 (2.6)

0

0.166

Outcome:

- Death

5 (13.2)

0

0.002