N

%

N

%

No of pts treated with rhEpo

268

No of pts with serum Epo levels <500 mIU/ml

217

93.5

No of pts evaluable for response

232

No of pts with serum Epo levels > 500 mIU/ml

15

6.5

Complete response

76

32.7

No of pts with serum Epo levels < 200 mIU/ml

145

62.5

Partial response

36

15.5

No of pts with serum Epo levels > 200 mIU/ml

87

37.5

Overall response

112

48.3

No of pts with a RAI value < 21

171

73.7

No response

120

51.7

No of pts with a RAI value > 21

61

26.3

Ability of serum Epo levels to predict responders

81/112

72.3

Ability of RAI to predict responders

107 /112

95.5

Serum Epo levels

Responseto anemia index

Type of response

<200 mIU/ml

%

>200 mIU/ml

%

RAI < 21

%

p

RAI > 21

%

p

CR

58/145

40.0

18/87

20.7

73/172

42.4

n.s.

3/60

5.0

<0.001

PR

23/145

15.9

13/87

14.9

34/172

19.8

n.s.

2/60

3.3

<0.001

OR

81/145

55.9

31/87

35.6

107/172

62.2

n.s.

5/60

8.3

<0.001

NR

64/145

44.1

56/87

74.4

65/172

37.8

n.s.

55/60

91.7

<0.001