Imaging Technology | Strengths | weaknesses |
Endoscopy | Biopsy is the gold standard for diagnosis, Endoscopy can visually observe the lesions and take biopsies. | When the lesion grows in the submucosa, it is prone to false negatives, leading to missed diagnosis. |
Endoscopic ultrasound | It can improve the accuracy of biopsy, and is the preferred method for local stage, which can be used for follow-up evaluation | Residual lesions are often overestimated in follow-up and in determining recurrence |
CT | Evaluates not only gastric lesions but also perigastric lymph nodes and adjacent tissue and organ involvement | CT is usually unable to display lymphoma confined to the mucosa |
MRI | Disease diagnosis and efficacy evaluation can be conducted through structural and functional information provided by DWI | Not suitable for patients with metal implants and claustrophobia |
PET/CT | Combining the advantages of morphological and functional imaging, it is widely used in the diagnosis, staging, efficacy evaluation, and recurrence detection. | MALT lymphoma may exhibit false negative results, while physiological uptake and inflammation may exhibit false positive results |
PET/MRI | Not inferior to PET/CT performance and far lower radiation levels than PET/CT | Failure to widely apply due to long inspection time and high use and maintenance costs |
Transabdominal ultrasound | It is a convenient, non-invasive, radiation free diagnostic method and a reasonable method for patients who require continuous monitoring, especially for patients who are not suitable for endoscopic ultrasound, such as the elderly | The value of transabdominal ultrasound for gastric lymphoma is still not clear enough because there are few domestic and international studies. |