Study | Sample Size | Tumor Type | Duration of Follow-Up | Number (%) with VA ≥20/40 at End of Follow-Up | Number (%) with VA ≥20/200 at End of Follow-Up | Alternate Measure of VA | Predictors of Poor VA after Treatment |
Bergman et al. 2005 [29] | 579 eyes | Choroidal and ciliary body melanomas | 3 and 5 years | 64/171 (37.2%) | 67/171 (39.2%) | -- | -- |
Sagoo et al. 2007 [10] | 37 patients | Circumpapillary choroidal melanoma | Mean 52 months, median 46 months | -- | 38% non-enucleated eyes | -- | -- |
Sagoo et al. 2008 [11] | 141 patients | Juxtapapillary choroidal melanoma overhanging optic disc | Mean 56 months | -- | 23% | -- | -- |
Finger et al. 2010 [30] | 384 patients | Uveal melanomas treated with Palladium-103 | Mean 47.2 months | -- | -- | Low and medium foveal doses: End median VA 20/25-20/30; High foveal dose: End median VA 20/80 | Foveal dose of radiation |
Gunduz et al. 2010 [12] | 24 patients | Choroidal melanoma treated with ruthenium brachytherapy alone | -- | 3/21 (14.2%) | 10/21 (47.6%) | -- | -- |
Verschueren et al. 2010 [13] | 430 patients | Choroidal melanoma | Median 50 months | -- | 283/430 (65.8%) | -- | Central tumors, juxtapapillary tumors |
Karlovits et al. 2011 [14] | 35 patients | Choroidal melanoma treated with iodine brachytherapy | Median 45 months | -- | 32% of patients with 3 or more years of follow-up | -- | -- |
Newman et al. 2011 [15] | 50 patients | Subfoveal choroidal melanomas with ≥6 months of follow-up | Median 54 months | 18/50 (36.0%) | 25/50 (50.0%) | -- | -- |
Finger et al. 2012 [16] | 24 patients | Choroidal melanomas within 1.5 mm of optic disc treated with slotted radiotherapy | Mean 23 months | 12/22 (55%) | 17/22 (77%) | -- | -- |
Berry et al. 2013 [17] | 82 patients | Medium sized choroidal melanomas | Median 46.8 months | 29/82 (35.4%) | 35/82 (42.7%) | -- | -- |
Caminal et al. 2013 [18] | 54 patients | Choroidal melanoma treated with iodine brachytherapy | Mean 59.47 months | -- | 19/54 (35.2%) | -- | -- |
Marconi et al. 2013 [31] | 94 patients | Choroidal melanoma treated with ruthenium brachytherapy | Median 39 months | 30% | 56% | -- | -- |
Semenova et al. 2013 [19] | 72 patients | Small choroidal melanomas | Mean 54 months | -- | 68/72 (94.4%) | -- | -- |
Sagoo et al. 2014 [32] | 650 eyes | Juxtapapillary choroidal melanoma | Median 40 months | -- | 46% at 5 years, 13% at 10 years | -- | Papillopathy, radiation cataract |
Semenova et al. 2014 [20] | 47 patients | T3 or T4 sized choroidal melanomas treated with palladium brachytherapy | Median 47 months |
| 25/47 (53%) | -- | -- |