Factor | H-VFA group | L-VFA group | p value | ||
(Before TACE) | n = 58 | n = 38 | |||
Age (years) | 71 | (41 - 87) | 71 | (55 - 83) | 0.784† |
Sex (male/female) | 37/21 | 24/14 | 0.950§ | ||
Height (cm) | 160.0 ± 9.8 | (138.5 - 179.0) | 160.2 ± 7.6 | (147.7 - 176.9) | 0.452* |
Body weight (kg) | 63.1 | (40.2 - 93.6) | 56.8 | (37.0 - 73.6) | 0.003† |
BMI (kg/m2) | 24.4 ± 2.6 | (20.1 - 30.2) | 22.2 ± 2.8 | (15.6 - 28.0) | 0.000* |
HBs Ag (+/−) | 7/51 | 5/33 | 1.000¶ | ||
HCV Ab (+/−) | 36/22 | 30/8 | 0.081§ | ||
Alcohol (over 20 g/day)(+/−) | 20/38 | 11/27 | 0.571§ | ||
Child's score (5, 6, 7, 8, 9) | 6 (5 - 9) | 7 (5 - 9) | 0.390† | ||
MELD score | 7.0 (6.0 - 12.3) | 7.3 (6.0 - 20.7) | 0.227† | ||
TNM stage of HCC (I, II, III, IVa, IVb) | 5/11/37/3/2 | 3/20/15/0/0 | 0.003* | ||
Past treatment frequency of TACE (times) | 1 (0 - 11) | 1 (0 - 10) | 0.283† | ||
Past treatments other than TACE (+/−) | 24/34 | 16/22 | 0.944§ | ||
Subcutaneous and intermuscular fat area (cm2/m2) | 59.8 ± 18.1 (33.6 - 97.8) | 44.4 ± 27.1 (2.8 - 101.4) | 0.001* | ||
Skeletal muscle area (cm2/m2) | 43.0 ± 8.7 (20.5 - 70.8) | 41.8 ± 7.2 (21.7 - 57.6) | 0.232* | ||
Sarcopenia (+/−) | 39/19 | 26/12 | 0.904§ | ||
PT (%) | 80.3 | (58.5 - 100.0) | 82.4 | (57.6 - 100.0) | 0.827† |
AST (IU/L) | 48 | (19 - 165) | 49 | (18 - 141) | 0.412† |
ALT (IU/L) | 36 | (11 - 111) | 37 | (13 - 130) | 0.875† |
γ-GTP (IU/L) | 51 | (20 - 857) | 47 | (10 - 1188) | 0.436† |
T-Bil (mg/dL) | 0.8 | (0.3 - 2.5) | 1.0 | (0.3 - 2.5) | 0.044† |
ChE (IU/L) | 161 | (81 - 348) | 145 | (47 - 327) | 0.123† |
Alb (g/dL) | 3.6 | (2.4 - 4.8) | 3.4 | (2.4 - 4.5) | 0.346† |
Prealbumin (mg/dL) | 11.5 | (4.2 - 28.2) | 10.9 | (4.5 - 33.1) | 0.479† |
BTR | 3.9 | (1.5 - 7.4) | 4.0 | (1.9 - 8.0) | 0.691† |
CRP | 0.1 | (0.1 - 6.1) | 0.1 | (0.1 - 2.9) | 0.401† |
Crn | 0.77 | (0.44 - 1.93) | 0.72 | (0.45 - 4.91) | 0.514† |
FPG (mg/dL) | 104 | (71 - 234) | 98 | (74 - 351) | 0.142† |
IRI (µU/mL) | 11 | (4 - 84) | 11 | (1 - 40) | 0.280† |
HOMA-IR | 2.8 | (0.81 - 43.30) | 2.64 | (0.19 - 20.80) | 0.310† |
HbA1c (%) | 5.6 | (4.4 - 8.2) | 5.1 | (4.3 - 10.2) | 0.017† |
ICG test retention rate at 15 min (%) | 25.4 | (5.5 - 59.5) | 23.4 | (3.5 - 75.6) | 0.919† |
Type 4 collagen 7S (ng/mL) | 6.5 | (3.0 - 14.0) | 7.8 | (3.6 - 16.0) | 0.132† |
HA (ng/mL) | 229 | (12.4 - 1483.6) | 332.9 | (48.1 - 1237.8) | 0.074† |
AFP (ng/mL) | 36 | (2 - 94260) | 26 | (5 - 14183) | 0.694† |
DCP | 250 | (14 - 688500) | 93 | (14 - 12749) | 0.076† |