Inclusion Criteria for Patients

Women (>18 yr old) who have survived primary breast cancer (with surgery, neo-adjuvant, adjuvant and/or radiation therapy) and are now presenting with either relapse or metastatic disease; or who presented with primary breast cancer and treated by mastectomy followed by chemotherapy and/or aromatase inhibitor therapy.

Exclusion Criteria for Patients

Men

Pre- or post-menopausal women without a personal history of breast cancer,

Women with untreated primary tumor breast cancer patients or did not going to undergo treatment at FHCI,

Individuals deemed not healthy enough to safely participate in the study by the study associated physicians.

Inclusion Criteria for Controls

Women >18 yr of age, who have never had and do not currently have breast cancer.

Exclusion Criteria for Controls

Men,

Pre- or post-menopausal women with a personal history of breast cancer,

Individuals deemed not healthy enough to safely participate in the study by the study associated physicians.