Before treatment

Increase (weeks of treatment)

Decrease (weeks of treatment)

500

1000 (1)

70 (4)

518

936 (6)

-

451

1009 (4)

631 (8)

525

1345 (4)

521 (8)

Mean

498.50 ± 33.37a

1072.50 ± 184.50b (3.75 ± 2.06)

407.33 ± 297.27c (6.67 ± 2.31)