| Domain of inquiry | Questions |
| Pre-enrollment attitudes and knowledge | How did you hear about the study? What did you hear about the study? What are some of the beliefs or stories (myths/conspiracies) about why this study is done in Botswana? |
| Participation and retention facilitators and barriers | What motivated you to join this study? What did you think the benefits of joining the study would be? What concerns did you have about joining the study? What challenges did you face while in the study? What are the difficulties you have faced in taking your pills? How have you managed to keep up with participation in the study? |
| Others’ reactions to study participation | Who have you told about your participation in the study? How have others reacted to your participation in the study? |