Group A n = 9

Group B n = 9

p-value

Sex (females/males)

4/5

4/6

0.26

Disease onset (years)

7.9 ± 0.8

13.3 ± 0.7

0.11

Age (years)

62.6 ± 2.8

79.1 ± 1.5

0.28

Stage according to Hoehn & Yahr scale

3

4

0.6

Schwab & England score (mean ± SD and n in each %)

62.0 ± 2.3

45.2 ± 3.1

<0.05

3 (60%)

5 (50%)

6 (70%)

4 (40%)

Disease duration (years)

OFF-time (h/12 h)

8.0 ± 0.4

13.0 ± 0.6

0.09

5.7 ± 0.2

6.4 ± 0.3

0.27

Levodopa

723 ± 15

920 ± 12

0.16

ON-time with dyskinesia (h/12 h)

3.5 ± 0.9

3.4 ± 0.2

0.4

Non-motor symptoms (NMSS)

44.2 ± 2.1

62.8 ± 3.2

0.1