E-group

E2 (pg/ml) pre-therapy

E2 (pg/ml) post-therapy

Age

R = 0.41

P = 0.028^*

R = 0.37

P = 0.06

HAM-A-14 scores

R = −0.27

P = 0.043^*

R = −0.24

P = 0.047^*

HAM-D scores

R = −0.65

P = 0.0001^*

R = −0.37

P = 0.036^*

MoCA-CA scores

R = 0.52

P = 0.047^*

P = 0.012

P = 0.015^*

HAM-D scores

R = −0.65

P = 0.0001^*

R = −0.37

P = 0.036^*

Increased scores of HAM-A

\

R = 0.21

P = 0.052^*

Increased scores of HAM-D

\

R = 0.35

P = 0.038^*