Additions and experimental conditions

dF/dt (g/s)

PKC (pmol/min/mg/protein)

NOS (pmol/g tissue wet wt)

Nitritos (μM)

cGMP (pmol/g tissue wet wt)

Basal normoxia

8.6 ± 0.6

1.3 ± 0.2

50 ± 4

75 ± 7

42 ± 3.2

ISO normoxia

13.4 ± 0.9^*

7.2 ± 0.4^*

200 ± 18^*

140 ± 12^*

99 ± 11.2^*

ISO + atenolol normoxia

8.4 ± 0.7

1.7 ± 0.5

65 ± 6

77 ± 8

47 ± 5.1

Basal hypoxia

5.6 ± 0.2

1.4 ± 0.2

52 ± 5

67 ± 6

43 ± 2.8

ISO hypoxia

7.1 ± 0.5^*

4.8 ± 0.3^*

220 ± 15^*

90 ± 8^*

104 ± 10.1^*

ISO + atenolol hypoxia

5.4 ± 0.4

1.3 ± 0.3

109 ± 9

70 ± 5

49 ± 5.9