Variable

NSCLC patients (%)

Healthy controls (%)

Total No.

160

160

Race

North Indians

North Indians

Gender

Males

124 (77.5)

124 (77.5)

Females

36 (22.5)

36 (22.5)

Age at diagnosis (years )

≤45 Y

32 (20.0)

32 (20.0)

>45 Y

128 (80.0)

128 (80.0)

Mean ± SD age (Y)

57.32 ± 11.9 (range, 30 - 85 years)

56.02 ± 10.6 (range, 32 - 80 years)

Smoking status

Non smoker

47 (29.4)

47 (29.4)

Smokers

113 (70.6)

113 (70.6)

Current smokers

48 (42.5)

48 (42.5)

Ex-smokers

65 (57.5)

65 (57.5)

Smoking level (pack year)

Mild (≤10)

18 (15.9)

18 (15.9)

Moderate (≤40)

49 (43.4)

49 (43.4)

Heavy (>40)

46 (40.7)

46 (40.7)

Smoking type

Cigarette

33 (29.2)

33 (29.2)

Bidi

16 (14.2)

16 (14.2)

Huka

27 (23.9)

27 (23.9)

Cigarette + Bidi

15 (13.3)

15 (13.3)

Cigarette + Huka

22 (19.5)

22 (19.5)

Histological type

Squamous cell carcinoma

79 (49.4)

Adenocarcinoma

81 (50.6)

TNM stage

Early (I & II)

60 (37.5)

Advanced (III & IV)

100 (62.5)

Distant metastases

Positive

42 (26.2)

Negative

118 (73.8)

Histological grades

Squamous cell carcinoma grades

Grade 1

43 (54.4)

Grade 2

22 (27.8)

Grade 3

14 (17.7)

Adenocarcinoma grade

Grade 1

14 (17.3)

Grade 2

23 (27.2)

Grade 3

45 (55.5)

Family history of any cancer

Significant

19 (11.9)

Non significant

141 (88.1)