Item | group | Early stage | Mid-stage | Recovery period | 2 weeks after discharge | F/Z | P |
CRP (mg/L) | 1 | 1.00 (0.70, 3.30) | 5.00 (1.00, 17.00)a | 2.40 (0.70, 2.40) | 1.10 (0.50, 2.40) | 6.012 | 0.001 |
2 | 12.25 (4.07, 43.05) | 18.95 (4.25, 33.87) | 2.65 (1.00, 13.95)b | 2.40 (1.10, 6.87)c | 3.049 | 0.034 | |
3 | 0.80 (0.50, 6.35) | 1.30 (0.50, 3.45) | 0.50 (0.50, 1.22) | 0.65 (0.50, 2.22) | 0.337 | 0.798 | |
TP (g/L) | 1 | 76.72 ± 5.21 | 71.28 ± 6.41a | 71.70 ± 4.96b | 74.26 ± 3.36c | 8.541 | <0.001 |
2 | 73.31 ± 8.21 | 69.33 ± 7.38 | 70.13 ± 6.95 | 73.70 ± 5.34 | 1.960 | 0.127 | |
3 | 71.48 ± 7.23 | 71.92 ± 6.21 | 71.60 ± 5.08 | 72.20 ± 4.73 | 0.060 | 0.981 | |
ALB (g/L) | 1 | 44.22 ± 5.06 | 40.55 ± 3.71a | 40.27 ± 3.86b | 41.36 ± 2.84c | 7.333 | 0.000 |
2 | 40.28 ± 6.62 | 37.41 ± .31 | 36.96 ± 4.38 | 39.30 ± 3.65 | 2.069 | 0.111 | |
3 | 44.42 ± 5.09 | 43.73 ± 4.35 | 42.98 ± 5.46 | 45.11 ± 5.02 | 0.665 | 0.576 | |
TBIL (umol/L) | 1 | 6.83 (5.00, 9.60) | 10.40 (6.71, 18.60)a | 7.80 (5.50, 12.51) | 7.23 (4.88, 9.03) | 3.475 | 0.018 |
2 | 7.50 (4.79, 9.95) | 14.85 (9.95, 20.42)a | 6.40 (4.67, 7.47) | 5.76 (4.45, 7.14) | 14.798 | <0.001 | |
3 | 9.39 (7.20, 13.31) | 11.10 (6.55, 14.96) | 11.19 (7.00, 14.43) | 12.01 (7.88, 15.09) | 0.275 | 0.844 | |
IBTL (U/L) | 1 | 4.77 (3.04, 6.60) | 7.40 (5.00, 12.90)a | 5.40 (3.60, 9.25) | 4.80 (3.80, 5.94) | 5.566 | 0.001 |
2 | 5.05 (3.13, 6.85) | 10.21 (7.10, 12.00)a | 4.40 (3.17, 5.38) | 4.01 (3.15, 5.76) | 14.168 | <0.001 | |
3 | 6.19 (4.32, 9.24) | 7.11 (4.25, 9.11) | 7.53 (4.93, 9.58) | 8.33 (5.76, 11.25) | 0.738 | 0.532 | |
DHIL (umol/L) | 1 | 2.16 (1.70, 3.00) | 3.80 (2.50, 6.20) | 2.54 (1.61, 4.10) | 2.17 (1.60, 2.95) | 1.280 | 0.284 |
2 | 2.60 (1.89, 3.17) | 5.05 (3.22, 6.14)a | 2.05 (1.43, 2.85) | 1.42 (1.25, 2.16) | 9.945 | <0.001 | |
3 | 3.57 (2.51, 4.24) | 3.82 (2.41, 5.63) | 3.33 (2.18, 4.96) | 3.15 (2.11, 4.60) | 0.237 | 0.871 | |
K+ (mmol/L) | 1 | 3.95 ± 0.34 | 4.08 ± 0.48 | 4.31 ± 0.32b | 4.15 ± 0.32c | 5.530 | 0.001 |
2 | 3.97 ± 0.60 | 3.71 ± 0.47 | 4.26 ± 0.37 | 4.07 ± 0.32 | 4.972 | 0.003 | |
3 | 3.87 ± 0.28 | 3.98 ± 0.35 | 4.07 ± 0.35 | 4.00 ± 0.27 | 1.385 | 0.254 | |
AMY (U/L) | 1 | 71.00 (54.30, 84.00) | 66.00 (51.80, 88.00) | 74.40 (61.60, 94.70) | 84.80 (60.50, 98.50)c | 1.376 | 0.253 |
2 | 59.00 (45.25, 83.57) | 56.00 (49.50, 78.50) | 76.25 (59.70, 113.82)b | 71.70 (54.55, 99.82)c | 4.009 | 0.011 | |
3 | 65.36 (53.57, 71.98) | 63.29 (53.50, 74.79) | 64.15 (53.57, 85.57) | 67.75 (53.57, 87.77) | 0.174 | 0.914 | |
CK (U/L) | 1 | 86.70 (66.00, 134.50) | 64.20 (56.10, 85.70)a | 60.50 (46.70, 76.50)b | 74.00 (61.70, 102.37) | 3.628 | 0.015 |
2 | 100.75 (71.95, 209.35) | 94.75 (56.02, 161.65) | 55.30 (32.07, 82.47)b | 65.80 (53.20, 99.02)c | 4.888 | 0.004 | |
3 | 78.68 (64.80, 124.60) | 70.15 (50.32, 90.26) | 67.10 (48.13, 78.10)b | 68.85 (50.57, 85.85)c | 1.032 | 0.383 | |
CK-MB (U/L) | 1 | 12.00 (10.00, 17.00) | 9.00 (7.00, 12.00)a | 9.40 (6.00, 14.00) | 13.00 (12.00, 16.00) | 5.212 | 0.002 |
2 | 14.00 (12.00, 20.75) | 12.00 (5.50, 14.75) | 9.00 (8.00, 12.00)b | 14.50 (11.25, 17.00) | 3.186 | 0.028 | |
3 | 12.00 (10.07, 16.25) | 11.17 (8.64, 13.79) | 11.00 (9.27, 12.35) | 10.33 (8.41, 15.82) | 1.814 | 0.152 | |
LDH (U/L) | 1 | 187.00 (174.20, 219.00) | 190.00 (163.31, 214.00) | 172.10 (155.00, 191.00) | 172.00 (153.00, 214.00) | 0.629 | 0.597 |
2 | 244.85 (199.50, 343.00) | 242.95 (197.25, 343.00) | 189.50 (156.25, 227.00)b | 177.50 (159.25, 226.00)c | 4.977 | 0.003 | |
3 | 180.06 (174.00, 207.25) | 177.77 (154.90, 215.14) | 167.98 (141.59, 181.50) | 171.11 (149.48, 184.71) | 1.630 | 0.190 | |
α-HBDH (U/L) | 1 | 147.00 (129.21, 167.50) | 137.50 (122.50, 150.00) | 125.00 (115.60, 158.90) | 146.00 (124.30, 177.80) | 0.659 | 0.578 |
2 | 173.55 (151.82, 268.00) | 170.20 (141.75, 247.10) | 139.00 (118.10, 183.72)b | 152.35 (130.07, 190.40)c | 2.678 | 0.053 | |
3 | 149.80 (140.53, 178.10) | 150.15 (130.00, 170.72) | 143.75 (124.60, 153.45) | 138.67 (124.92, 148.34)c | 2.338 | 0.080 | |
Limited daily activity score | 1 | 2.40 (1.10, 5.00) | 3.20 (2.00, 4.70) | 2.700 (1.40, 4.50) | 3.30 (2.70, 4.60) | 0.346 | 0.792 |
2 | 12.00 (9.25, 15.00) | 10.50 (9.25, 14.25) | 6.50 (5.00, 11.75) | 5.00 (5.00, 7.00)c | 5.254 | 0.002 | |
3 | 6.50 (5.00, 9.50) | 5.00 (5.00, 6.00) | 5.00 (5.00, 5.00) | 5.00 (5.00, 5.00)c | 2.079 | 0.110 | |
Symptom score of dyspnea | 1 | 10.00 (7.00, 15.00) | 9.00 (7.00, 11.00) | 7.00 (6.00, 8.00)b | 6.00 (5.00, 6.00)c | 11.658 | <0.001 |
2 | 9.50 (7.00, 13.50) | 10.00 (9.25, 13.50) | 9.00 (6.25, 10.00) | 6.00 (5.25, 7.75)c | 5.066 | 0.003 | |
3 | 7.00 (6.00, 12.00) | 6.00 (5.00, 9.75) | 5.50 (5.00, 6.50)b | 5.50 (5.00, 5.00)c | 4.115 | 0.009 | |
Psychological and emotional score | 1 | 14.00 (12.00, 17.00) | 13.00 (10.00, 16.00) | 8.00 (7.00, 10.00)b | 7.00 (6.00, 8.00)c | 31.167 | <0.001 |
2 | 14.50 (14.00, 18.75) | 14.00 (12.00, 17.75) | 10.00 (8.00, 12.00)b | 7.00 (6.00, 8.75)c | 16.759 | <0.001 | |
3 | 10.00 (8.25, 14.50) | 7.00 (6.00, 11.50) | 6.50 (6.00, 7.75)b | 6.00 (6.00, 6.75)c | 6.275 | 0.001 | |
Imaging CT score | 1 | 3.00 (3.00, 3.00) | 2.00 (2.00, 3.00)a | 2.00 (1.00, 2.00)b | 1.00 (1.00, 1.00)c | 67.601 | <0.001 |
2 | 3.00 (3.00, 3.00) | 3.00 (2.00, 3.00) | 1.00 (1.00, 2.00)b | 1.00 (1.00, 1.00)c | 40.475 | <0.001 | |
3 | 3.00 (2.00, 3.00) | 2.00 (2.00, 3.00) | 1.00 (1.00, 2.00)b | 1.00 (1.00, 1.00)c | 19.335 | <0.001 | |
Nucleic acid positivity rate | 1 | 31 (88.57) | 20 (57.14)a | 0 (0.00)b | 1 (2.86)c | 79.674 | <0.001 |
2 | 20 (100.00) | 11 (55.00)a | 0 (0.00)b | 0 (0.00)c | 58.405 | <0.001 | |
3 | 20 (100.00) | 16 (80.00)a | 0 (0.00)b | 0 (0.00)c | 66.232 | <0.001 |