Item | Early stage | Mid-stage | Recovery period | 2 weeks after discharge | F/Z | P |
WBC (109/L) | 6.20 (4.50, 7.20) | 6.00 (4.60, 7.80) | 6.40 (5.10, 7.50) | 6.70 (6.00, 7.70)c | 1.999 | 0.114 |
RBC (1012/L) | 4.77 ± 0.74 | 4.58 ± 0.82 | 4.51 ± 0.83b | 4.56 ± 0.74 | 1.563 | 0.198 |
PLT (109/L) | 228.00 (193.00, 294.00) | 259.00 (215.00, 315.00) | 273.00 (234.00, 319.00)b | 250.00 (221.00, 291.00) | 2.627 | 0.051 |
LYMGH (109/L) | 1.30 (1.00, 1.70) | 1.50 (1.00, 1.90) | 1.70 (1.20, 2.10)b | 1.90 (1.60, 2.30)c | 1.810 | 0.145 |
NEUT (109/L) | 4.30 (3.00, 5.21) | 3.70 (2.80, 5.40) | 3.70 (3.00, 5.10) | 4.10 (3.50, 4.70) | 0.117 | 0.950 |
HGB (g/L) | 138.58 ± 23.00 | 133.90 ± 21.02 | 131.64 ± 22.86 | 134.37 ± 21.68 | 1.282 | 0.281 |
CRP (mg/L) | 3.00 (0.80, 9.00) | 4.00 (1.00, 18.30) | 1.40 (0.50, 4.00) | 1.10 (0.50, 2.70)c | 5.219 | 0.002 |
TP (g/L) | 74.41 ± 6.95 | 70.93 ± 6.62a | 71.26 ± 5.55b | 73.56 ± 4.36 | 6.181 | <0.001 |
ALB (g/L) | 43.22 ± 5.73 | 40.56 ± 4.62a | 40.11 ± 4.93b | 41.81 ± 4.28 | 6.035 | 0.001 |
GLO (g/L) | 31.20 ± 6.72 | 30.10 ± 6.27 | 31.13 ± 5.22 | 31.71 ± 5.45 | 0.959 | 0.412 |
ALT (U/L) | 26.00 (17.00, 45.00) | 26.20 (17.00, 39.00) | 27.00 (18.00, 46.00) | 25.00 (17.00, 44.00) | 0.226 | 0.878 |
AST (U/L) | 25.70 (20.90, 35.00) | 24.00 (19.00, 32.00) | 22.00 (18.00, 28.00) | 23.00 (18.00, 30.30) | 1.639 | 0.180 |
TBIL (umol/L) | 7.70 (5.00, 10.62) | 11.70 (8.57, 16.90)a | 7.40 (5.50, 12.77) | 7.23 (5.21, 10.51) | 8.087 | <0.001 |
IBTL (U/L) | 4.97 (3.45, 6.90) | 7.90 (5.17, 11.50)a | 5.15 (3.53, 8.51) | 5.40 (3.78, 7.66) | 10.183 | <0.001 |
DHIL (umol/L) | 2.60 (1.90, 3.66) | 4.00 (2.72, 5.88)a | 2.60 (1.72, 4.18) | 2.17 (1.42, 3.20) | 3.935 | 0.009 |
TBA (umol/L) | 3.10 (1.60, 7.30) | 3.10 (2.00, 4.70) | 3.50 (1.60, 5.20) | 4.10 (2.90, 5.90) | 0.768 | 0.513 |
UREA (mmol/L) | 4.10 (3.26, 5.10) | 4.51 (3.54, 5.85) | 5.00 (3.60, 6.21) | 3.49 (3.12, 4.21) | 0.599 | 0.616 |
CREA (umol/L) | 65.80 (54.10, 79.20) | 70.50 (59.90, 83.00) | 69.70 (52.63, 79.10) | 59.70 (48.50, 71.60) | 2.098 | 0.101 |
UA (umol/L) | 291.00 (240.00, 373.00) | 293.00 (233.00, 373.00) | 298.00 (257.00, 365.00) | 314.00 (268.00, 388.00) | 0.913 | 0.435 |
GLU (mmol/L) | 5.71 (5.17, 6.64) | 5.28 (4.79, 6.84) | 5.01 (4.68, 5.83)b | 5.23 (4.67, 6.23) | 1.542 | 0.204 |
Ca2+ (mmol/L) | 2.24 ± 0.16 | 2.22 ± 0.16 | 2.26 ± 0.13 | 2.26 ± 0.10 | 1.613 | 0.187 |
K+ (mmol/L) | 3.93 ± 0.41 | 3.95 ± 0.47 | 4.23 ± 0.35b | 4.09 ± 0.31c | 9.277 | <0.001 |
CI− (mmol/L) | 103.30 ± 3.05 | 102.98 ± 3.22 | 104.03 ± 2.85 | 103.00 ± 2.61 | 2.082 | 0.103 |
Na+ (mmol/L) | 139.01 ± 2.99 | 138.31 ± 3.31 | 138.67 ± 2.75 | 139.07 ± 2.37 | 1.113 | 0.344 |
(mmol/L) | 29.05 ± 5.51 | 29.99 ± 4.46 | 29.87 ± 4.25 | 29.87 ± 3.98 | 0.666 | 0.573 |
AG (mmol/L) | 9.55 (7.53, 12.84) | 8.06 (6.13, 12.49) | 8.11 (5.88, 12.57)b | 10.37 (7.50, 12.84) | 2.578 | 0.054 |
STY (mOsm/L) | 286.17 ± 5.92 | 284.39 ± 8.83 | 286.34 ± 5.23 | 287.02 ± 4.46 | 2.362 | 0.071 |
AMY (U/L) | 65.00 (53.00, 83.90) | 63.30 (51.00, 79.60) | 70.10 (57.00, 94.70)b | 78.50 (57.00, 97.00)c | 2.725 | 0.044 |
CK (U/L) | 86.70 (66.80, 141.20) | 70.00 (55.80, 98.00) | 60.50 (42.10, 77.30)b | 70.60 (54.30, 97.40)c | 3.333 | 0.020 |
CK-MB (U/L) | 13.00 (10.00, 17.00) | 10.00 (7.00, 13.00)a | 10.00 (7.00, 12.00)b | 13.00 (10.21, 16.00) | 7.713 | <0.001 |
LDH (U/L) | 198.00 (177.10, 231.50) | 194.64 (169.00, 235.00) | 175.00 (152.00, 200.00)b | 175.00 (154.00, 211.00)c | 5.168 | 0.002 |
α-HBDH (U/L) | 153.60 (134.00, 179.00) | 144.00 (132.00, 175.40) | 137.00 (119.00, 160.00)b | 144.73 (127.60, 162.00)c | 3.623 | 0.014 |
Limited daily activity score | 9.00 (6.00, 14.00) | 9.00 (5.00, 11.00) | 5.00 (5.00, 7.00)b | 5.00 (5.00, 5.00)c | 15.531 | <0.001 |
Symptom score of dyspnea | 9.00 (7.00, 14.00) | 9.00 (6.00, 11.00) | 6.00 (5.00, 9.00)b | 6.00 (5.00, 6.00)c | 18.543 | <0.001 |
Psychological and emotional score | 14.00 (11.00, 17.00) | 12.00 (9.00, 16.00)a | 8.00 (7.00, 11.00)b | 7.00 (6.00, 8.00)c | 45.168 | <0.001 |
Imaging CT score | 3.00 (2.00, 3.10) | 2.00 (2.00, 3.00)a | 2.00 (1.00, 2.00)b | 1.00 (1.00, 1.00)c | 120.379 | <0.001 |
Nucleic acid positivity rate | 72 (96.00) | 47 (62.67) | 0 (0.00)b | 1 (1.33)c | 202.213 | <0.001 |