Lung Volume Subdivisions | GOLD Stage | P-value†| |||
1 (n = 98) | 2 (n = 150) | 3 (n = 60) | 4 (n = 23) | ||
FVC, liters | 3.8 ± 0.9 | 3.1 ± 0.9 | 2.3 ± 0.7 | 1.9 ± 0.7 | <0.001 |
FVC, % pred | 104.2 ± 12.6 | 84.8 ± 14.6 | 64.9 ± 14.3 | 48.1 ± 16.8 | <0.001 |
SVC, liters | 3.9 ± 1.0 | 3.2 ± 0.8 | 2.6 ± 0.8 | 2.3 ± 0.6 | <0.001 |
SVC, % pred | 106.5 ± 14.6 | 87.6 ± 14.2 | 71.5 ± 16.1 | 55.8 ± 14.1 | <0.001 |
FEV1, liters | 2.5 ± 0.6 | 1.7 ± 0.5 | 1.1 ± 0.3 | 0.7 ± 0.2 | <0.001 |
FEV1, % pred | 93.5 ± 10.6 | 65.7 ± 8.6 | 39.6 ± 5.7 | 22.9 ± 5 | <0.001 |
FEV1/FVC | 0.65 ± 0.04 | 0.58 ± 0.08 | 0.45 ± 0.11 | 0.35 ± 0.13 | <0.001 |
TLC, liters | 6.2 ± 1.3 | 5.8 ± 1.3 | 5.8 ± 1.7 | 6.6 ± 2.1 | 0.04 |
TLC, % pred | 111.2 ± 17.1 | 104.4 ± 18.9 | 105.8 ± 23.4 | 106.9 ± 28.6 | 0.07 |
FRC, liters | 3.5 ± 0.8 | 3.5 ± 0.9 | 3.9 ± 1.3 | 5.3 ± 1.8 | <0.001 |
FRC, % pred | 113.3 ± 26.3 | 115.0 ± 25.7 | 131.4 ± 35.4 | 153.6 ± 44.7 | <0.001 |
RV, liters | 2.3 ± 0.7 | 2.7 ± 0.8 | 3.2 ± 1.2 | 4.4 ± 1.6 | <0.001 |
RV, % pred | 122.4 ± 38.3 | 141.8 ± 39.8 | 172.3 ± 54.9 | 221.2 ± 70.9 | <0.001 |
IC, liters | 2.7 ± 0.8 | 2.3 ± 0.6 | 1.8 ± 0.6 | 1.3 ± 0.4 | <0.001 |
IC, % pred | 107.9 ± 21.3 | 92.4 ± 18.1 | 73.9 ± 18.6 | 48.5 ± 13.1 | <0.001 |
IC/SVC | 0.70 ± 0.11 | 0.74 ± 0.13 | 0.72 ± 0.11 | 0.60 ± 0.14 | 0.002 |
IC/TLC | 0.43 ± 0.07 | 0.39 ± 0.07 | 0.31 ± 0.07 | 0.20 ± 0.04 | <0.001 |
FRC/TLC | 0.57 ± 0.07 | 0.61 ± 0.07 | 0.69 ± 0.07 | 0.80 ± 0.04 | <0.001 |
RV/TLC | 0.38 ± 0.09 | 0.46 ± 0.09 | 0.57 ± 0.08 | 0.67 ± 0.06 | <0.001 |
SVC/FVC | 1.01 ± 0.07 | 1.01 ± 0.09 | 1.06 ± 0.11 | 1.02 ± 0.13 | <0.001 |