Age (years) | Cyclophosphamide dose reduction (per pulse, mg/kg) IV Mesna given to minimize toxicity | |
| eGFR > 30 ml | eGFR < 30 ml |
<60 | 15 | 12.5 |
60 - 70 | 12.5 | 10 |
>70 | 10 | 7.5 |