First positive

First negative

Second positive

Second negative

Total subjects, n (%)

1304 (100)

24,292 (100)

516 (100)

12,481 (100)

Cancer^a, n (%)

12 (1.0)

8 (0.03)

8 (1.6)

5 (0.04)

Benign disease^b, n (%)

89 (6.8)

83 (0.3)

34 (6.6)

35 (0.3)