First positive

First negative

Second positive

Second negative

Subjects, n (%)

1304 (5)

24,292 (95)

516 (4)

12,481 (96)

Sex, n (%)

Male

930 (71)

14,952 (62)

353 (68)

7641 (61)

Female

374 (29)

9340 (38)

163 (32)

4840 (39)

Mean agea, y

49.1

45.9

49.5

47.1

IQR Agea, y

40 - 59

37 - 55

40 - 59

39 - 55

Age categorya, n (%)

20 - 29 y

11 (0.8)

447 (1.8)

1 (0.2)

56 (0.4)

30 - 39 y

300 (23)

7623 (31)

106 (21)

3416 (27)

40 - 49 y

315 (24)

6805 (28)

143 (28)

3875 (31)

50 - 59 y

395 (30)

6247 (26)

152 (30)

3513 (28)

60 - 69 y

248 (19)

2894 (12)

107 (21)

1514 (12)

70 - 75 y

16 (1.2)

132 (0.5)

5 (1.0)

75 (0.6)

Employeeb, n (%)

1049 (80)

17,526 (72)

404 (78)

8914 (71)